Research on Decreasing the Intestinal Carriage of Antibiotic Resistant Bacteria
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 3268
Special Issue Editor
Special Issue Information
Dear Colleagues,
The intestinal microbiota is a major reservoir of multidrug-resistant bacteria (MDRB). Intestinal colonization by MDRB is promoted by intestinal dysbiosis and may evolve from an asymptomatic carriage to various infections including urinary, gastrointestinal and bloodstream infections. Furthermore, the intestinal carriage of MDRB can lead to environmental contamination and transmission to healthy or diseased subjects. Hence, treatments to decrease this carriage are crucial in order to limit the global spread of antimicrobial resistance. Various strategies have been assessed, but none has proved to be effective so far.
The aim of this Issue is to explore new approaches able to fight such a carriage of MDRB, particularly carbapenem and ESBL-producing Escherichia coli, Klebsiella pneumoniae, and Enterobacter cloacae, but also vancomycin-resistant enterococci and other relevant species. A diversity of strategies will be welcome: for example, the use of prebiotics, of probiotics (in particular new probiotics), the development of new quorum-sensing inhibitors, the synthesis of new prodrugs to specifically target MDRB, the use of bacteriophages, fecal transplantation, the beneficial effect of some diets, etc. Articles on the better use of antibiotics will also be considered, particularly those on the methodologies able to prevent intestinal dysbiosis.
Prof. Dr. Michel Dion
Guest Editor
Keywords
- prebiotic
- probiotic
- antibiotic-resistant bacteria
- intestinal carriage
- quorum-sensing inhibitor
- bacteriophage
- prodrug
- E. coli
- K. pneumoniae
- enterococci
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