Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
7.4
4.2
Journals
Molecules
Special Issues
Functional Nanomaterials for Biosensors and Biomedicine Application
molecules-logo
Submit to Special Issue Submit Abstract to Special Issue Review for Molecules Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Functional Nanomaterials for Biosensors and Biomedicine Application

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Applied Chemistry".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 3996

Special Issue Editors

Prof. Dr. Liqiang Luo

E-Mail Website
Guest Editor
Department of Chemistry, College of Sciences, Shanghai University, Shanghai 200444, China
Interests: electrochemistry; biosensors; bioimaging and bioanalysis; environmental analysis; food analysis
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Xiaoqiang Liu

E-Mail Website
Guest Editor
College of Chemical and Molecular Sciences, Henan University, Kaifeng 475004, China
Interests: synthesis and application of nanocomposites in electrochemical and photoelectrochemical biosensors

Special Issue Information

Dear Colleagues,

Functional nanomaterials refer to nanomaterials with diverse compositions, structures, and morphologies. Taking advantage of their unique properties of small-size effects, surface effects, and quantum-size effects, functional nanomaterials have found amazing applications in the fields of biosensing, bioimaging, and biomedicine.

This Special Issue focuses on recent achievements in functional nanomaterials for biosensors and biomedicine applications. We invite original contributions, as well as review articles, related to the rational design, synthesis, and application of novel functional nanomaterials with unique properties (such as carbon dots, metal-organic frameworks, novel two-dimensional nanomaterials, etc.) in biosensors and biomedicine.

Prof. Dr. Liqiang Luo
Prof. Dr. Xiaoqiang Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • functional nanomaterials
  • biosensors
  • biomedicine
  • drug delivery
  • biotherapy

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

11 pages, 3073 KiB  
Article
Au Nanoshell-Based Lateral Flow Immunoassay for Colorimetric and Photothermal Dual-Mode Detection of Interleukin-6
by Congying Wen, Yue Dou, Yao Liu, Xuan Jiang, Xiaomei Tu and Ruiqiao Zhang
Molecules 2024, 29(15), 3683; https://doi.org/10.3390/molecules29153683 - 3 Aug 2024
Cited by 2 | Viewed by 1136
Abstract
Interleukin-6 (IL-6) detection and monitoring are of great significance for evaluating the progression of many diseases and their therapeutic efficacy. Lateral flow immunoassay (LFIA) is one of the most promising point-of-care testing (POCT) methods, yet suffers from low sensitivity and poor quantitative ability, [...] Read more.
Interleukin-6 (IL-6) detection and monitoring are of great significance for evaluating the progression of many diseases and their therapeutic efficacy. Lateral flow immunoassay (LFIA) is one of the most promising point-of-care testing (POCT) methods, yet suffers from low sensitivity and poor quantitative ability, which greatly limits its application in IL-6 detection. Hence, in this work, we integrated Aushell nanoparticles (NPs) as new LFIA reporters and achieved the colorimetric and photothermal dual-mode detection of IL-6. Aushell NPs were conveniently prepared using a galvanic exchange process. By controlling the shell thickness, their localized surface plasmon resonance (LSPR) peak was easily tuned to near-infrared (NIR) range, which matched well with the NIR irradiation light. Thus, the Aushell NPs were endowed with good photothermal effect. Aushell NPs were then modified with IL-6 detection antibody to construct Aushell probes. In the LFIA detection, the Aushell probes were combined with IL-6, which were further captured by the capture IL-6 antibody on the test line of the strip, forming a colored band. By observation with naked eyes, the colorimetric qualitative detection of IL-6 was achieved with limit of 5 ng/mL. By measuring the temperature rise of the test line with a portable infrared thermal camera, the photothermal quantitative detection of IL-6 was performed from 1~1000 ng/mL. The photothermal detection limit reached 0.3 ng/mL, which was reduced by nearly 20 times compared with naked-eye detection. Therefore, this Aushell-based LFIA efficiently improved the sensitivity and quantitative ability of commercial colloidal gold LFIA. Furthermore, this method showed good specificity, and kept the advantages of convenience, speed, cost-effectiveness, and portability. Therefore, this Aushell-based LFIA exhibits practical application potential in IL-6 POCT detection. Full article
(This article belongs to the Special Issue Functional Nanomaterials for Biosensors and Biomedicine Application)
►▼ Show Figures

Figure 1

13 pages, 5409 KiB  
Article
A Dopamine Detection Sensor Based on Au-Decorated NiS2 and Its Medical Application
by Chongchong Ma, Yixuan Wen, Yuqing Qiao, Kevin Z. Shen and Hongwen Yuan
Molecules 2024, 29(12), 2925; https://doi.org/10.3390/molecules29122925 - 20 Jun 2024
Viewed by 1176
Abstract
This article reports a simple hydrothermal method for synthesizing nickel disulfide (NiS2) on the surface of fluorine-doped tin oxide (FTO) glass, followed by the deposition of 5 nm Au nanoparticles on the electrode surface by physical vapor deposition. This process ensures [...] Read more.
This article reports a simple hydrothermal method for synthesizing nickel disulfide (NiS2) on the surface of fluorine-doped tin oxide (FTO) glass, followed by the deposition of 5 nm Au nanoparticles on the electrode surface by physical vapor deposition. This process ensures the uniform distribution of Au nanoparticles on the NiS2 surface to enhance its conductivity. Finally, an Au@NiS2-FTO electrochemical biosensor is obtained for the detection of dopamine (DA). The composite material is characterized using transmission electron microscopy (TEM), UV-Vis spectroscopy, X-ray diffraction, and X-ray photoelectron spectroscopy. The electrochemical properties of the sensor are investigated using cyclic voltammetry (CV), differential pulse voltammetry (DPV), and time current curves in a 0.1 M PBS solution (pH = 7.3). In the detection of DA, Au@NiS2-FTO exhibits a wide linear detection range (0.1~1000 μM), low detection limit (1 nM), and fast response time (0.1 s). After the addition of interfering substances, such as glucose, L-ascorbic acid, uric acid, CaCl2, NaCl, and KCl, the electrode potential remains relatively unchanged, demonstrating its strong anti-interference capability. It also demonstrates strong sensitivity and reproducibility. The obtained Au@NiS2-FTO provides a simple and easy-to-operate example for constructing nanometer catalysts with enzyme-like properties. These results provide a promising method utilizing Au coating to enhance the conductivity of transition metal sulfides. Full article
(This article belongs to the Special Issue Functional Nanomaterials for Biosensors and Biomedicine Application)
►▼ Show Figures

Figure 1

Review

Jump to: Research

22 pages, 5498 KiB  
Review
Application of the Electrospinning Technique in Electrochemical Biosensors: An Overview
by Jie Liu, Zhong Dong, Ke Huan, Zhangchu He, Qixian Zhang, Dongmei Deng and Liqiang Luo
Molecules 2024, 29(12), 2769; https://doi.org/10.3390/molecules29122769 - 11 Jun 2024
Cited by 3 | Viewed by 1397
Abstract
Electrospinning is a cost-effective and flexible technology for producing nanofibers with large specific surface areas, functionalized surfaces, and stable structures. In recent years, electrospun nanofibers have attracted more and more attention in electrochemical biosensors due to their excellent morphological and structural properties. This [...] Read more.
Electrospinning is a cost-effective and flexible technology for producing nanofibers with large specific surface areas, functionalized surfaces, and stable structures. In recent years, electrospun nanofibers have attracted more and more attention in electrochemical biosensors due to their excellent morphological and structural properties. This review outlines the principle of electrospinning technology. The strategies of producing nanofibers with different diameters, morphologies, and structures are discussed to understand the regulation rules of nanofiber morphology and structure. The application of electrospun nanofibers in electrochemical biosensors is reviewed in detail. In addition, we look towards the future prospects of electrospinning technology and the challenge of scale production. Full article
(This article belongs to the Special Issue Functional Nanomaterials for Biosensors and Biomedicine Application)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop