Lipid Carriers in Drug Delivery
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Macromolecular Chemistry".
Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 2693
Special Issue Editor
Interests: polymers; high molecular weight lipids; micro- and nano-carriers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lipid carriers are interesting drug delivery systems since they are able to encapsulate a large variety of drugs and modulate their drug release kinetics. Due to their size, biocompatibility, and safety, they can be administered via different routes, including the oral, parenteral, topical, pulmonary, nasal, and ophthalmic ones. Remarkably, these lipid carriers are able to enhance solubility, absorption, and, consequently, the bioavailability of poorly soluble active drugs, meaning that they represent an important delivery option for this class of drugs. Different types of delivery systems, including liposomes, solid lipid nanoparticles, nanostructured lipid carriers, lipid–polymer hybrid nanoparticles, and lipoplexes, can be formulated depending on the lipid/excipient selected and the preparative method used.
We are pleased to invite you to contribute to the Special Issue entitled “Lipid Carriers in Drug Delivery", which aims to discuss the recent advances concerning the administration of drugs, both natural and synthetic active drugs, via the use of lipid-based carriers. Hence, in this context, this Special Issue will hopefully act as a forum for the presentation of rigorous research studies, reviews, and communications relevant to all the aspects of the vectorization of selected active substances, including the preparation, properties, and applications of lipid-based carriers.
In this Special Issue, emphasis will be placed on different lipid-based carrier systems, particularly those in nanostructured forms, and the advantages they offer, including improved solubility, absorption, and bioavailability. In particular, we wish to foster collaboration between researchers involved in the manufacturing of different carrier systems, with a view to upscaling their feasibility. Therefore, original research articles and reviews on gene delivery using charged lipids and the delivery of herbal actives and nutraceuticals are welcome, as well as scientific papers on commercial products based on the lipid technology and recent patents in this area.
Concerning the endpoints of the obtained drug delivery carriers, diagnosis, prevention, or therapeutic purposes need to be cohesive in order to yield significant effects in terms of human or veterinary health. Finally, the role of the well-characterized lipid vehicles must be a major part of submitted works, not a peripheral topic.
This Special Issue is structured around the following focal points:
- The design and formulation of lipid-based drug carriers: This theme emphasizes the design, formulation, and engineering of lipid-based drug carriers, encompassing liposomes, lipid nanoparticles, micelles, and more. It explores their structural and physicochemical properties.
- Targeted and controlled drug delivery: This Special Issue will investigate the utilization of lipid carriers for site-specific and controlled drug release, contributing to enhanced therapeutic outcomes.
- Lipid carriers in nanomedicine: We will explore the interdisciplinary field of nanomedicine, where lipid-based drug carriers have revolutionized drug delivery in various medicinal applications, including cancer therapy and diagnostics.
- Innovations in lipid carrier synthesis and characterization: This topic spotlights innovations in the synthesis of lipid carriers and advanced characterization techniques, ensuring their reliability and scalability.
The formation of this Special Issue provides a comprehensive platform for researchers, pharmacologists, and pharmaceutical scientists to share their latest findings and innovations regarding the field of lipid-based drug carriers. We anticipate contributions that shed light on the vital role of these carriers in optimizing drug delivery, reducing side effects, and revolutionizing the landscape of pharmaceuticals.
Dr. Adriana Trapani
Guest Editor
Manuscript Submission Information
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Keywords
- lipid carriers
- solid lipid nanoparticles (SLNs)
- nanostructured lipid carriers (NLCs)
- liposomes
- gene delivery
- cancer therapy
- diagnostics
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