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Biofilms: Recent Development and Novel Strategies to Combat Infections

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Applied Chemistry".

Deadline for manuscript submissions: closed (15 November 2022) | Viewed by 10944

Special Issue Editor


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Guest Editor
The Novo Nordisk Foundation, Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark
Interests: bio-nanotechnology; mettalic annoparticles; antimicorbial applications; biofilm; cancer; drugs
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Special Issue Information

Dear Colleagues,

Biofilms are one of the biggest concern for medical society, environment, food and other sectors. It caused by bacterial adhesion and proliferation, which is a serious and increasing concerns in everyday life, and are responsible for significant damage in several industries, including textile, water treatment, marine transport, medicine and food packaging. The cells inside biofilms are surrounded by an exopolymeric matrix that protects them against different external stresses. Notwithstanding the enormous efforts of academic researchers and industry, a general solution for restricting bacterial colonization remains to be found. Therefore, new strategies for controlling bacteria activity are urgently needed and nanomaterials constitute a very promising approach. This Special Issue plans to give an overview of the most recent advances in the field of antibacterial nanomaterials and their applications in diverse areas. This Special Issue is aimed at providing selected contributions on advances in the synthesis, characterization, and applications of nanomaterials with regard to biofilm inhibition activity. Potential topics include, but are not limited to:
Antimicrobial nanoparticles;
Biofilm inhibition;
Biofilm formation and damage;
Antibacterial nanocoatings and nanocomposites;
Mechanisms of action;
Future perspectives for antimicrobial nanomaterials;
Role of antimicrobial nanomaterials in medicine.

Dr. Priyanka Singh
Guest Editor

Manuscript Submission Information

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Keywords

  • Biofilms
  • Nanomaterials
  • Antimicrobial
  • nanoparticles
  • nanocoating
  • nanocomposites

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Published Papers (1 paper)

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Review

29 pages, 813 KiB  
Review
Antimicrobial Mechanisms and Clinical Application Prospects of Antimicrobial Peptides
by Xin Li, Siyao Zuo, Bin Wang, Kaiyu Zhang and Yang Wang
Molecules 2022, 27(9), 2675; https://doi.org/10.3390/molecules27092675 - 21 Apr 2022
Cited by 72 | Viewed by 10297
Abstract
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and are components of the innate immunity of almost all living things. They play an important role in resisting foreign invading microorganisms. Antimicrobial peptides have a wide range of antibacterial [...] Read more.
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and are components of the innate immunity of almost all living things. They play an important role in resisting foreign invading microorganisms. Antimicrobial peptides have a wide range of antibacterial activities against bacteria, fungi, viruses and other microorganisms. They are active against traditional antibiotic-resistant strains and do not easily induce the development of drug resistance. Therefore, they have become a hot spot of medical research and are expected to become a new substitute for fighting microbial infection and represent a new method for treating drug-resistant bacteria. This review briefly introduces the source and structural characteristics of antimicrobial peptides and describes those that have been used against common clinical microorganisms (bacteria, fungi, viruses, and especially coronaviruses), focusing on their antimicrobial mechanism of action and clinical application prospects. Full article
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