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Mass Spectrometry-Based Techniques in Food and Natural Product Analysis

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 1911

Special Issue Editors


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Guest Editor
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, Università degli Studi di Messina, Messina, Italy
Interests: food chemistry; natural products; bioactive compounds; liquid chromatography; mass spectrometry; ambient mass spectrometry; direct-MS analysis
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy
Interests: food chemistry; nutraceuticals; phytochemistry; phytocomplexes; antiaging; inflammation; antimicrobial; antiviral
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nowadays, consumers pay increasing attention to high-quality foods from a defined geographical origin as a guarantee of healthiness and food safety. In the same way, there is a growing global interest in natural products, not merely as food sources but also for their industrial value in the cosmetic, pharmaceutical and manufacturing sectors. These products are associated with health benefits for humans due to their high phytochemical content and antioxidant and antimicrobial activities, and are attractive due to their sensory and textural properties.

Many efforts have been made toward the development of accurate and reliable analytical methods useful for safety and quality evaluation as well as the establishment of the authenticity and traceability of foodstuffs and natural products. These analytical strategies comprise various untargeted and targeted approaches employed for marker compound identification, detection of adulterated materials, and/or for the analysis of secondary metabolites (polyphenols, carotenoids, glucosinolates, alkaloids etc.) playing essential roles in crop yield and nutritional quality control, which contribute to color, taste, aroma, and other specific traits essential as authenticity markers or geographical provenience.

In this framework, mass spectrometry (MS) represents a valid tool, whether used alone or combined with chromatographic techniques, and is widely employed in food and agricultural industry and research laboratories for quality control analyses. Continuous improvements have been made in the related instrumentation, leading to the introduction of alternative and innovative MS-based techniques. 

MS-based targeted approaches focus on the identification of a set of known and specific metabolites, such as phytochemicals belonging to a defined chemical class or quantification of one or more analytical targets for “profiling” and natural products and food quality control. Conversely, untargeted analysis or “fingerprinting” simultaneously detects numerous unspecified targets or data points, and has been successfully applied for matrix authentication, origin traceability, and consequently the detection of fraudulent activities.

We welcome, for the present Special Issue, review articles and original research papers presenting advances and applications of MS-based methods in targeted and untargeted analysis of food and natural matrices, in order to provide an overview of the state of the art and recent innovations in the field.

Dr. Domenica Mangraviti
Prof. Dr. Matteo Micucci
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food analysis
  • natural products
  • chromatography
  • mass spectrometry
  • targeted
  • untargeted
  • profiling
  • fingerprinting

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Published Papers (1 paper)

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Research

14 pages, 3147 KiB  
Article
Analysis of Pesticide Residues on Fruit Using Swab Spray Ionization Mass Spectrometry
by Thomas Michael Muggli and Stefan Schürch
Molecules 2023, 28(18), 6611; https://doi.org/10.3390/molecules28186611 - 14 Sep 2023
Cited by 2 | Viewed by 1540
Abstract
The vast quantity and high variety of pesticides globally used in agriculture entails considerable risks for the environment and requires ensuring the safety of food products. Therefore, powerful analytical tools are needed to acquire qualitative and quantitative data for monitoring pesticide residues. The [...] Read more.
The vast quantity and high variety of pesticides globally used in agriculture entails considerable risks for the environment and requires ensuring the safety of food products. Therefore, powerful analytical tools are needed to acquire qualitative and quantitative data for monitoring pesticide residues. The development of ambient ionization mass spectrometry methods in the past two decades has demonstrated numerous ways to generate ions under atmospheric conditions and simultaneously to reduce the need for extended sample preparation and circumvent chromatographic separation prior to mass analysis. Swab spray ionization enables the generation of ions directly from swabs via the application of high voltage and solvent flow. In this study, swab sampling of fruit surfaces and subsequent ionization directly from the swab in a modified electrospray ion source was employed for the screening and quantitation of pesticide residues. Aspects regarding sample collection, sampling efficacy on different surfaces, and swab background are discussed. The effect of solvent composition on pesticide-sodium adduct formation and the suppression of ionization by the background matrix have been investigated. Furthermore, a novel approach for the quantitation of pesticide residues based on depletion curve areas is presented. It is demonstrated that swab spray ionization is an effective and quick method for spectral library-based identification and the quantitative analysis of polar contact pesticide residues on food. Full article
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