Mass Spectrometry Imaging 2021
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 354
Special Issue Editor
2. National Human Reproduction Laboratory, University of Pécs, 7624 Pécs, Hungary
3. ELKH-PTE Human Reproduction Research Group, University of Pécs, 7624 Pécs, Hungary
Interests: mass spectrometry; imaging mass spectrometry; embryogenesis; cancer diagnosis; andrology; fertilization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
One of the most exciting developments in the last few decades is the use of mass spectrometry as an imaging method, in which a histological section and matrix of 10-20 microns are dried on a sample holder. Thousands of mass spectra are then taken from the sample in a predetermined manner and with laser intensity; these are then displayed as images, using the appropriate software, based on the distribution of intensities for each m/z value. Imaging is an unlabeled technique that allows us to examine the localization of up to hundreds of molecules within a tissue in a single measurement and display them in 2D or even 3D. It also makes proteins, lipids and metabolites visible. The main advantages of mass spectrometry imaging for studying molecules’ location and distribution within tissue are that this analytical technique requires a small sample, and it can provide greater selectivity, more information and improved accuracy compared to others.
All researchers working in the field are cordially invited to contribute original research papers, short communications or reviews to this Special Issue of Molecules.
Dr. Laszlo MarkGuest Editor
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Keywords
- biomarker discovery
- clinical pathology
- laser ablation
- lipidomics
- molecular imaging
- proteomics
- tissue section
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