Mass Spectrometry Imaging
A special issue of Methods and Protocols (ISSN 2409-9279).
Deadline for manuscript submissions: closed (31 December 2019) | Viewed by 6768
Special Issue Editor
2. National Human Reproduction Laboratory, University of Pécs, 7624 Pécs, Hungary
3. ELKH-PTE Human Reproduction Research Group, University of Pécs, 7624 Pécs, Hungary
Interests: mass spectrometry; imaging mass spectrometry; embryogenesis; cancer diagnosis; andrology; fertilization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mass spectrometry imaging (MSI) makes the possibility of combining histological information with a label-free mass spectrometric imaging technology. MSI has emerged as an important tool to visualize the spatial distributions of even hundreds of biomolecules, directly from the sample surface. Various ionization techniques have been implemented for molecular imaging of biological tissue sections. Secondary ion mass spectrometry (SIMS) and matrix assisted laser desorption ionization (MALDI) mass spectrometry are the most widely-used MSI methods, both of which require vacuum conditions. Ambient ionization MSI techniques have grown rapidly in the past decade as well, enabling the analysis under atmospheric pressure with minimum or no sample preparation. In vivo and in situ MSI have become approachable with the advent of ambient ionization sources, such as laser ablation electrospray ionization (LAESI), desorption electrospray ionization (DESI), desorption atmospheric pressure photoionization (DAPPI), probe electrospray ionization (PESI), nanospray desorption electrospray ionization (nanoDESI), etc. MSI facilitates the simultaneous imaging of small metabolites, lipids, polypeptides, and large proteins in tissue sections. Soft ionization yields minimum fragmentation attributing to its relative low energy deposition and thus keeps the biomolecules intact. MSI has been extensively applied in different fields including pharmaceutical drug development, biochemistry, forensic science, clinical research, and biomarker discovery.
In this Special Issue on “Mass Spectrometry Imaging”, we welcome researchers to submit both original research manuscripts, as well as review papers, on all areas of in vitro and in vivo Imaging Mass Spectrometry. The goal of this Special Issue is to collect the most recent state of the art technological developments, applications, sample pre-treatment protocols and data analysis workflows in this emerging scientific field.
Dr. Laszlo Mark
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Methods and Protocols is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- imaging
- mass spectrometry
- MALDI
- SIMS
- LAESI
- DESI
- tissue section
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
