Embryonic Development and Differentiation: 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 1921
Special Issue Editor
2. National Human Reproduction Laboratory, University of Pécs, 7624 Pécs, Hungary
3. ELKH-PTE Human Reproduction Research Group, University of Pécs, 7624 Pécs, Hungary
Interests: mass spectrometry; imaging mass spectrometry; embryogenesis; cancer diagnosis; andrology; fertilization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This is a continuation of the Special Issue “Embryonic Development and Differentiation”.
Human infertility is a global problem with significant social and economic impact. Successful pregnancy is a complex process comprising unique events, including fertilization, implantation, decidualization, placentation, and birth. Nowadays, assisted reproduction technologies (ARTs) have provided a remarkable impact on successful pregnancy after in vitro fertilization. However, these methods are associated with a relatively low clinical pregnancy rate of approximately 30% per transfer. The uterus’s receptive phase is marked by the endometrium’s structural and functional maturation. This is a limited time span when the blastocyst competency is superimposed on the receptive endometrium. It is well-known that the lipid and protein metabolism and signaling of early-stage pregnancy are vital in successful embryogenesis. However, embryo–maternal molecular communication is poorly understood, nor is it understood whether IVF’s low take-home baby outcome results from some abnormal molecular networking.
This Special Issue calls for original articles and reviews that will provide the readers of IJMS with a comprehensive elucidation of fertilization, embryonic development, and molecular networking during embryogenesis.
Dr. László Márk
Guest Editor
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Keywords
- blastocyte
- embryogenesis
- endometrium
- implantation
- in vitro fertilization (IFV)
- ICSI
- oocyte
- pregnancy
- seminal plasma
- sperm
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