The Role of Nutrition in Dermato-Endocrine Disorders—Towards a New Concept of ‘DermoNutrition’
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".
Deadline for manuscript submissions: closed (25 October 2024) | Viewed by 213
Special Issue Editors
Interests: food science; nutraceutical; nutrition; metabolism; polyphenols; antioxidants; oxidative stress; inflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
It is well-known that there is a seminal interconnection between certain dermatological diseases (e.g., acne, psoriasis, and hidradenitis suppurativa) and endocrine disorders such as thyroid dysfunction, polycystic ovary syndrome (PCOS), metabolic syndrome, and obesity. The latter is identified as a contributing factor, causing an imbalance in adipokine levels resulting in increased inflammation. The management of these comorbidities includes achieving various outcomes such as controlling glucose metabolism and optimising vitamin D levels, which influence inflammation and immunity. Moreover, vitamin D deficiency is itself associated with endocrine disorders such as insulin resistance and PCOS. Also, some skin diseases are linked to alterations in thyroid function. Overall, these reports emphasise the importance of a multidisciplinary approach to effectively manage both skin diseases and associated endocrine disorders.
Furthermore, recent studies described a link between skin diseases and intestinal disorders, such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). It is hypothesised, in fact, that a leaky gut condition, i.e., a morpho-functional alteration of the intestinal barrier, can activate the local immune system, causing inflammation and worsening the symptoms of skin diseases. This relationship suggests an involvement of the gut–skin axis in the pathogenesis of these disorders.
In addition to drug therapies, it is, therefore, essential to advise patients with dermatological diseases on lifestyle changes (such as diet and exercise) as part of a holistic approach. Such approaches aim to manage inflammation and comorbidities. Diet plays, in this context, a significant role in the management of skin disorders by identifying dietary patterns and/or foods and their components that may have a positive or negative impact on skin health.
The present Special Issue welcomes the submission of papers either describing original research (in vitro, ex vivo, and animal-based studies or clinical trials) or scientific literature reviewing (including narrative reviews, systematic reviews, meta-analyses, and opinion papers) covering novel insights on the role played by diet (or foods/food components) in the management of dermatological diseases with an endocrine implication. Papers describing novel mechanisms of action/targets and/or novel associations will be profoundly appreciated.
Dr. Giuseppe Annunziata
Prof. Dr. Giuseppe Argenziano
Guest Editors
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Keywords
- diet
- nutrition
- nutraceutical
- polyphenols
- food components
- dermatological disorders
- endocrine disorders
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