Mycobacterium tuberculosis Pathogenesis, Diagnosis and Treatment
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (31 May 2024) | Viewed by 1571
Special Issue Editor
Interests: infection and immunity; host-pathogen interaction; bacterial pathogenesis; toxins; Mycobacterium tuberculosis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mycobacterium tuberculosis (Mtb) is a contagious and airborne bacterial pathogen. It causes tuberculosis (TB), which is one of the leading infectious diseases worldwide. It is estimated that Mtb latently infects one-third of the world’s population and accounts for ~2 million of death worldwide each year. While the past decades have seen while many efforts made to reduce the global TB burden, TB has remained one of the major threats to public health. Mtb invades human by air and establishes infection in lung, using many different virulence factors as its defense mechanisms against the host immune responses. Unfortunately, however, the mechanisms of Mtb virulence are largely unknown, and emergence of multidrug resistant Mtb strains and co-infection of Mtb with HIV has posed new challenges in TB control. There is an urgent need to enhance our understanding of Mtb pathogenesis and develop novel and effective countermeasures against the disease.
In this Special Issue, we plan to highlight the most recent advances in the studies of Mtb pathogenesis, diagnosis, and treatment. The Special Issue will cover, but is not limited to: investigation of the mechanism of Mtb pathogenesis, identification and characterization of new virulence genes/factors, host–pathogen interaction, development and utilization of new methods, technologies, model organisms for the study of Mtb pathogenesis and development of new diagnostic and treatment approaches. We expect that this Special Issue will greatly enhance our understanding of Mtb pathogenesis and facilitate the development of new diagnostics and treatments.
Dr. Jianjun Sun
Guest Editor
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Keywords
- Mycobacterium tuberculosis
- pathogenesis
- diagnosis
- treatment
- host-pathogen interaction
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