Calcium Channels as Therapeutic Targets
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 1182
Special Issue Editors
Interests: electrophysiology; voltage-gated calcium channels; cannabinoids; ion channels; GPCRs; pain; ataxia
Special Issues, Collections and Topics in MDPI journals
Interests: acetylcholine nicotinic receptors; voltage-gated ion channels; venom peptides; conotoxins; structure-function relationship; electrophysiology; nociception
Special Issues, Collections and Topics in MDPI journals
Interests: calcium channels; TRPC channels; ion channels
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Ion channels are key modulators of intracellular levels of Ca2+, which, in turn, is a vital physiological ‘second messenger’. Whether modulated through voltage changes, endogenous ligands/protein partners, and/or changes to Ca2+ levels, different Ca2+ channel families represent key molecular targets in a range of pathophysiologies that carry a heavy health, well-being, and economic burden. Thus, Ca2+ channels are major targets in diseases, including pain, epilepsy, neurodegenerative disorders, and neuropsychiatric disorders. Understanding and treating these diseases is increasingly relevant in today’s aging society.
This Special Issue will shed light on new pharmacological agents that modulate different classes of Ca2+ channels, including voltage-gated and transient receptor potential channels and/or the auxiliary subunits that make up the protein complex. We welcome submissions from diverse fields of studies, including, but not limited to, the development of small molecular entities and biological drugs, the development of toxins from the plant and animal kingdoms, the exploitation of knowledge of Ca2+ channel structure and function, and genetic studies of channelopathies and disease association.
Prof. Dr. Gary J. Stephens
Prof. Dr. David Adams
Dr. Hussein N. Rubaiy
Guest Editors
Manuscript Submission Information
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Keywords
- voltage-gated Ca2+ channels
- TRP channels
- Ca2+-permeable TRP and ASIC channels
- STIM/orai channels
- Ca2+ channel structure and function
- Ca2+ channel toxins
- Ca2+ channelopathies
- neuropharmacology
- pain
- epilepsy
- neurodegenerative and neuropsychiatric disorders
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