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Polymers
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Polymer-Based Composites for Biomedical Applications
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Polymer-Based Composites for Biomedical Applications

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (20 October 2023) | Viewed by 7028

Special Issue Editors

Dr. Bong Joo Park

E-Mail Website
Guest Editor
Department of Electrical and Biological Physics, Institute of Biomaterials, Kwangwoon University, Seoul 01897, Republic of Korea
Interests: biomaterials for biomedical applications; biological safety evaluation of biomaterials including nanomaterials; tissue engineering; photodynamic therapy using nanomaterials; drug delivery using nebulizer
Special Issues, Collections and Topics in MDPI journals
Dr. Jae Ho Shin

E-Mail Website
Guest Editor
Department of Chemistry, KwangWoon University, Seoul 01897, Republic of Korea
Interests: biomaterials for biomedical applications; biodegradable nanofibers for tissue engineering; biocompatible polymeric composites for implantable devices; organic–inorganic hybrid drug delivery nanoparticles

Special Issue Information

Dear Colleagues,

The importance of polymeric materials/composites has been recently recognized in biomedical fields such as cancer therapy, antimicrobial agents, and drug delivery, and new natural and synthetic-based polymers have been widely developed and used for biomedical applications.

This Special Issue aims to present a collection of original research papers and reviews on polymeric materials/composites for biomedical applications.

Topics of interest include:

  • Biocompatible polymeric composites;
  • Polymeric composites with antimicrobial activity;
  • Functionalized/multi-functionalized polymeric composites;
  • Therapeutic polymeric composites;
  • Smart polymeric composites;
  • Polymeric carriers for drug delivery.

Dr. Bong Joo Park
Dr. Jae Ho Shin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biopolymers
  • biocompatible natural/synthetic polymers
  • polymer-based nanomaterials/composites
  • functionalized polymeric composites
  • smart polymeric materials/composites
  • polymeric carriers for drug delivery

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Published Papers (3 papers)

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Research

14 pages, 4977 KiB  
Article
Fabrication of CuO-NP-Doped PVDF Composites Based Electrospun Triboelectric Nanogenerators for Wearable and Biomedical Applications
by Bindhu Amrutha, Gajula Prasad, Ponnan Sathiyanathan, Mohammad Shamim Reza, Hongdoo Kim, Madhvesh Pathak and Arun Anand Prabu
Polymers 2023, 15(11), 2442; https://doi.org/10.3390/polym15112442 - 25 May 2023
Cited by 14 | Viewed by 2533
Abstract
A flexible and portable triboelectric nanogenerator (TENG) based on electrospun polyvinylidene fluoride (PVDF) doped with copper oxide (CuO) nanoparticles (NPs, 2, 4, 6, 8, and 10 wt.-% w.r.t. PVDF content) was fabricated. The structural and crystalline properties of the as-prepared PVDF-CuO composite membranes [...] Read more.
A flexible and portable triboelectric nanogenerator (TENG) based on electrospun polyvinylidene fluoride (PVDF) doped with copper oxide (CuO) nanoparticles (NPs, 2, 4, 6, 8, and 10 wt.-% w.r.t. PVDF content) was fabricated. The structural and crystalline properties of the as-prepared PVDF-CuO composite membranes were characterized using SEM, FTIR, and XRD. To fabricate the TENG device, the PVDF-CuO was considered a tribo-negative film and the polyurethane (PU) a counter-positive film. The output voltage of the TENG was analyzed using a custom-made dynamic pressure setup, under a constant load of 1.0 kgf and 1.0 Hz frequency. The neat PVDF/PU showed only 1.7 V, which further increased up to 7.5 V when increasing the CuO contents from 2 to 8 wt.-%. A decrease in output voltage to 3.9 V was observed for 10 wt.-% CuO. Based on the above results, further measurements were carried out using the optimal sample (8 wt.-% CuO). Its output voltage performance was evaluated as a function of varying load (1 to 3 kgf) and frequency (0.1 to 1.0 Hz) conditions. Finally, the optimized device was demonstrated in real-time wearable sensor applications, such as human motion and health-monitoring applications (respiration and heart rate). Full article
(This article belongs to the Special Issue Polymer-Based Composites for Biomedical Applications)
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16 pages, 3310 KiB  
Article
Polyvinylidene Fluoride/Aromatic Hyperbranched Polyester of Third-Generation-Based Electrospun Nanofiber as a Self-Powered Triboelectric Nanogenerator for Wearable Energy Harvesting and Health Monitoring Applications
by Ramadasu Gunasekhar, Ponnan Sathiyanathan, Mohammad Shamim Reza, Gajula Prasad, Arun Anand Prabu and Hongdoo Kim
Polymers 2023, 15(10), 2375; https://doi.org/10.3390/polym15102375 - 19 May 2023
Cited by 13 | Viewed by 2119
Abstract
Flexible pressure sensors have played an increasingly important role in the Internet of Things and human–machine interaction systems. For a sensor device to be commercially viable, it is essential to fabricate a sensor with higher sensitivity and lower power consumption. Polyvinylidene fluoride (PVDF)-based [...] Read more.
Flexible pressure sensors have played an increasingly important role in the Internet of Things and human–machine interaction systems. For a sensor device to be commercially viable, it is essential to fabricate a sensor with higher sensitivity and lower power consumption. Polyvinylidene fluoride (PVDF)-based triboelectric nanogenerators (TENGs) prepared by electrospinning are widely used in self-powered electronics owing to their exceptional voltage generation performance and flexible nature. In the present study, aromatic hyperbranched polyester of the third generation (Ar.HBP-3) was added into PVDF as a filler (0, 10, 20, 30 and 40 wt.% w.r.t. PVDF content) to prepare nanofibers by electrospinning. The triboelectric performances (open-circuit voltage and short-circuit current) of PVDF-Ar.HBP-3/polyurethane (PU)-based TENG shows better performance than a PVDF/PU pair. Among the various wt.% of Ar.HBP-3, a 10 wt.% sample shows maximum output performances of 107 V which is almost 10 times that of neat PVDF (12 V); whereas, the current slightly increases from 0.5 μA to 1.3 μA. The self-powered TENG is also effective in measuring human motion. Overall, we have reported a simpler technique for producing high-performance TENG using morphological alteration of PVDF, which has the potential for use as mechanical energy harvesters and as effective power sources for wearable and portable electronic devices. Full article
(This article belongs to the Special Issue Polymer-Based Composites for Biomedical Applications)
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10 pages, 2048 KiB  
Article
In Vitro and In Vivo Protective Effects of Agaro-Oligosaccharides against Hydrogen Peroxide-Stimulated Oxidative Stress
by Lei Wang, Xiaoting Fu, Jimin Hyun, Jiachao Xu, Xin Gao and You-Jin Jeon
Polymers 2023, 15(7), 1612; https://doi.org/10.3390/polym15071612 - 23 Mar 2023
Cited by 3 | Viewed by 1822
Abstract
In our previous research, we investigated the anti-inflammatory activity of the agaro-oligosaccharides prepared from the agar of Gracilaria lemaneiformis (AO). In the present study, in order to further explore the bioactivities of AO, the antioxidant activity of AO was investigated in vitro in [...] Read more.
In our previous research, we investigated the anti-inflammatory activity of the agaro-oligosaccharides prepared from the agar of Gracilaria lemaneiformis (AO). In the present study, in order to further explore the bioactivities of AO, the antioxidant activity of AO was investigated in vitro in Vero cells and in vivo in zebrafish. AO scavenged alkyl, 1,1-diphenyl-2-picrylhydrazyl, and hydroxyl radicals at the IC50 value of 4.86 ± 0.13, 3.02 ± 0.44, and 1.33 ± 0.05 mg/mL, respectively. AO significantly suppressed hydrogen peroxide (H2O2)-stimulated oxidative damage by improving cell viability. This happened via suppressing apoptosis by scavenging intracellular reactive oxygen species (ROS). Furthermore, the in vivo results displayed that AO protected zebrafish against H2O2-stimulated oxidative damage by reducing the levels of intracellular ROS, cell death, and lipid peroxidation in a dose-dependent manner. These results indicate that AO effectively alleviated in vitro and in vivo oxidative damage stimulated by H2O2, and suggest the potential of AO in the cosmetic and functional food industries. Full article
(This article belongs to the Special Issue Polymer-Based Composites for Biomedical Applications)
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