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Polymers
Special Issues
Electrospun Nanofibers for Medical and Bio Applications
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Electrospun Nanofibers for Medical and Bio Applications

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: 15 May 2025 | Viewed by 4246

Special Issue Editor

Dr. Tomasz Kowalczyk

E-Mail Website
Guest Editor
Laboratory of Polymers and Biomaterials, Institute of Fundamental Technological Research, Polish Academy of Sciences (IPPT PAN), 02-106 Warsaw, Poland
Interests: electrospun polymer fibers; scaffolds for tissue engineering; internal and external wound dressings; drug delivery systems; medical devices; nanofiber post-processing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Electrospinning is one of the most effective methods of micro-and nanomaterial production. It has a comparably very high throughput, enabling the construction of materials of different types of polymers. Fragile biomolecules, drugs, or even living cells can be electrospun or electrosprayed. As micro-and nanofibers can mimic the natural environment of the living cells, they can be used in many biological and medical applications. These include tissue engineering, medical devices, internal and external wound dressings, drug delivery systems, and artificial tissues. Electrospun nonwovens can be post modified to attain desired properties.This Special Issue highlights the current research progress of electrospinning applied to produce materials of biological and medical importance. 

Dr. Tomasz Kowalczyk
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrospun polymer fibers
  • electrospun nanofiber post-processing
  • tissue engineering
  • polymeric scaffolds
  • internal and external wound dressings
  • drug delivery systems
  • co-axial and multi-axial electrostatic techniques
  • medical devices
  • artificial tissues

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Published Papers (2 papers)

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Research

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14 pages, 4403 KiB  
Article
Virucidal PVP-Copper Salt Composites against Coronavirus Produced by Electrospinning and Electrospraying
by João de Deus Pereira de Moraes Segundo, Jamilly Salustiano Ferreira Constantino, Guilherme Bedeschi Calais, Celso Fidelis de Moura Junior, Maria Oneide Silva de Moraes, Jéssica Heline Lopes da Fonseca, Junko Tsukamoto, Rodolpho Ramilton de Castro Monteiro, Fábia Karine Andrade, Marcos Akira d’Ávila, Clarice Weis Arns, Marisa Masumi Beppu and Rodrigo Silveira Vieira
Polymers 2022, 14(19), 4157; https://doi.org/10.3390/polym14194157 - 4 Oct 2022
Cited by 3 | Viewed by 2047
Abstract
Electrospinning technology was used to produced polyvinylpyrrolidone (PVP)-copper salt composites with structural differences, and their virucidal activity against coronavirus was investigated. The solutions were prepared with 20, 13.3, 10, and 6.6% w/v PVP containing 3, 1.0, 0.6, and 0.2% w/ [...] Read more.
Electrospinning technology was used to produced polyvinylpyrrolidone (PVP)-copper salt composites with structural differences, and their virucidal activity against coronavirus was investigated. The solutions were prepared with 20, 13.3, 10, and 6.6% w/v PVP containing 3, 1.0, 0.6, and 0.2% w/v Cu (II), respectively. The rheological properties and electrical conductivity contributing to the formation of the morphologies of the composite materials were observed by scanning electron microscopy (SEM). SEM images revealed the formation of electrospun PVP-copper salt ultrafine composite fibers (0.80 ± 0.35 µm) and electrosprayed PVP-copper salt composite microparticles (1.50 ± 0.70 µm). Energy-dispersive X-ray spectroscopy (EDS) evidenced the incorporation of copper into the produced composite materials. IR spectra confirmed the chemical composition and showed an interaction of Cu (II) ions with oxygen in the PVP resonant ring. Virucidal composite fibers inactivated 99.999% of coronavirus within 5 min of contact time, with moderate cytotoxicity to L929 cells, whereas the virucidal composite microparticles presented with a virucidal efficiency of 99.999% within 1440 min of exposure, with low cytotoxicity to L929 cells (mouse fibroblast). This produced virucidal composite materials have the potential to be applied in respirators, personal protective equipment, self-cleaning surfaces, and to fabric coat personal protective equipment against SARS-CoV-2, viral outbreaks, or pandemics. Full article
(This article belongs to the Special Issue Electrospun Nanofibers for Medical and Bio Applications)
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Review

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30 pages, 6280 KiB  
Review
Piezoelectric Scaffolds as Smart Materials for Bone Tissue Engineering
by Angelika Zaszczyńska, Konrad Zabielski, Arkadiusz Gradys, Tomasz Kowalczyk and Paweł Sajkiewicz
Polymers 2024, 16(19), 2797; https://doi.org/10.3390/polym16192797 - 2 Oct 2024
Viewed by 1248
Abstract
Bone repair and regeneration require physiological cues, including mechanical, electrical, and biochemical activity. Many biomaterials have been investigated as bioactive scaffolds with excellent electrical properties. Amongst biomaterials, piezoelectric materials (PMs) are gaining attention in biomedicine, power harvesting, biomedical devices, and structural health monitoring. [...] Read more.
Bone repair and regeneration require physiological cues, including mechanical, electrical, and biochemical activity. Many biomaterials have been investigated as bioactive scaffolds with excellent electrical properties. Amongst biomaterials, piezoelectric materials (PMs) are gaining attention in biomedicine, power harvesting, biomedical devices, and structural health monitoring. PMs have unique properties, such as the ability to affect physiological movements and deliver electrical stimuli to damaged bone or cells without an external power source. The crucial bone property is its piezoelectricity. Bones can generate electrical charges and potential in response to mechanical stimuli, as they influence bone growth and regeneration. Piezoelectric materials respond to human microenvironment stimuli and are an important factor in bone regeneration and repair. This manuscript is an overview of the fundamentals of the materials generating the piezoelectric effect and their influence on bone repair and regeneration. This paper focuses on the state of the art of piezoelectric materials, such as polymers, ceramics, and composites, and their application in bone tissue engineering. We present important information from the point of view of bone tissue engineering. We highlight promising upcoming approaches and new generations of piezoelectric materials. Full article
(This article belongs to the Special Issue Electrospun Nanofibers for Medical and Bio Applications)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: 3D printed Polylactic acid/Hydroxyapatite (PLA/HA) and Polylactic acid/Gold (PLA/AU) scaffolds dedicated to bone tissue regeneration
Authors: Angelika Zaszczynska1, Tomasz Kowalczyk1, Ewelina Zabost2, Paweł Ł. Sajkiewicz1, Dorota Kołbuk1
Affiliation: 1:Institute of Fundamental Technological Research, Lab. Polymers & Biomaterials, Polish Academy of Sciences, Pawinskiego 5b St., 02-106 Warsaw, Poland 2: The University of Warsaw Biological and Chemical Research Centre, Żwirki i Wigury 101 St., 02-089 Warsaw, Poland

Title: Piezoelectric Scaffolds as Smart Materials for Bone Tissue Engineering
Authors: Angelika Zaszczyńska; Konrad Zabielski; Arkadiusz Gradys; Tomasz Kowalczyk; Paweł Ł. Sajkiewicz
Affiliation: Laboratory of Polymers and Biomaterials, Institute of Fundamental Technological Research, Polish Academy of Sciences, Pawińskiego 5B, 02-106 Warsaw, Poland
Abstract: Bone repair and regeneration require physiological cues, including mechanical, electrical, and biochemical activity. Many biomaterials have been investigated as bioactive scaffolds with excellent electrical properties. Amongst biomaterials, piezoelectric materials (PM) are gaining attention in biomedicine, power harvesting, biomedical devices, and structural health monitoring. PM have unique properties, such as the ability to affect physiological movements and deliver electrical stimuli to damaged bone or cells without an external power source. The crucial bone property is its piezoelectricity. Bones can generate electrical charges and potential in response to mechanical stimuli, as they influence bone growth and regeneration. Piezoelectric materials respond to human microenvironment stimuli and are an important factor in bone regeneration and repair. This manuscript is an overview of the fundamentals of the materials generating the piezoelectric effect and their influence on bone repair and regeneration. The paper focuses on the state of the art of piezoelectric materials, such as polymers, ceramics, and composites, and their application in bone tissue engineering. We present important information from the point of view of bone tissue engineering. We highlight the promising upcoming approaches and new generations of piezoelectric materials.

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