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Synthesis and Sensor Applications of Hybrid Bionanomaterials

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 8479

Special Issue Editors


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Guest Editor
College of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, China
Interests: two-dimensional nanomaterials; supramolecular self-assembly; nanomaterials; biomedical engineering; sensors and biosensors
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Faculty of Mathematics, Physics and Informatics, Comenius University, Mlynská dolina F1, 842 48 Bratislava, Slovakia
Interests: biosensors; DNA aptamers; electrochemistry; molecular acoustics; model membranes; nanomaterials; nanoparticles
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The design and synthesis of structure- and function-specific nanomaterials has made great contributions to the development of novel sensors and biosensors for various applications in biomedicine, food analysis, environmental monitoring, gas sensing, and others. Recently, more efforts have been made to create hybrid bionanomaterials for promoting their sensor applications. For instance, many biological molecules like DNA, proteins, peptides, enzymes, viruses, and biopolymers have been combined with other functional nanomaterials such as carbon nanotubes, graphene, graphene-like two-dimensional materials, nanoparticles, quantum dots, and some others to form functional hybrid bionanomaterials, which have also shown wide applications for the fabrication of electrochemical, electronic, fluorescent, spectroscopic, colorimetric, and mechanical force sensors for the detection of metallic ions, drugs, small molecules, biomacromolecules, cells, cancer biomarkers, and gases.

To present recent advancements in this developing field, here we would like to invite contributions from scientists who are actively involved in research related to the design, synthesis, and sensor/biosensor applications of various hybrid bionanomaterials.

Prof. Dr. Gang Wei
Prof. Dr. Tibor Hianik
Guest Editors

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Keywords

  • sensors and biosensors
  • biomimetic synthesis
  • synthesis methods
  • hybrid nanomaterials
  • organic hybrids
  • inorganic hybrids
  • 2D materials
  • nanoparticles
  • nanofibers
  • scaffolds
  • electrochemical sensors
  • fluorescent sensors
  • electronic sensors
  • label-free sensors
  • metallic ions
  • drugs
  • small molecules
  • biomacromolecules
  • cells
  • cancer biomarkers

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Published Papers (2 papers)

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Review

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33 pages, 4003 KiB  
Review
Electrochemical Aptasensors Based on Hybrid Metal-Organic Frameworks
by Gennady Evtugyn, Svetlana Belyakova, Anna Porfireva and Tibor Hianik
Sensors 2020, 20(23), 6963; https://doi.org/10.3390/s20236963 - 5 Dec 2020
Cited by 20 | Viewed by 4284
Abstract
Metal-organic frameworks (MOFs) offer a unique variety of properties and morphology of the structure that make it possible to extend the performance of existing and design new electrochemical biosensors. High porosity, variable size and morphology, compatibility with common components of electrochemical sensors, and [...] Read more.
Metal-organic frameworks (MOFs) offer a unique variety of properties and morphology of the structure that make it possible to extend the performance of existing and design new electrochemical biosensors. High porosity, variable size and morphology, compatibility with common components of electrochemical sensors, and easy combination with bioreceptors make MOFs very attractive for application in the assembly of electrochemical aptasensors. In this review, the progress in the synthesis and application of the MOFs in electrochemical aptasensors are considered with an emphasis on the role of the MOF materials in aptamer immobilization and signal generation. The literature information of the use of MOFs in electrochemical aptasensors is classified in accordance with the nature and role of MOFs and a signal mode. In conclusion, future trends in the application of MOFs in electrochemical aptasensors are briefly discussed. Full article
(This article belongs to the Special Issue Synthesis and Sensor Applications of Hybrid Bionanomaterials)
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Other

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12 pages, 3151 KiB  
Letter
An Electrochemical Sensor Based on Chalcogenide Molybdenum Disulfide-Gold-Silver Nanocomposite for Detection of Hydrogen Peroxide Released by Cancer Cells
by Jinchun Hu, Congcong Zhang, Xue Li and Xin Du
Sensors 2020, 20(23), 6817; https://doi.org/10.3390/s20236817 - 28 Nov 2020
Cited by 21 | Viewed by 3486
Abstract
Hydrogen peroxide (H2O2) as a crucial signal molecule plays a vital part in the growth and development of various cells under normal physiological conditions. The development of H2O2 sensors has received great research interest because of [...] Read more.
Hydrogen peroxide (H2O2) as a crucial signal molecule plays a vital part in the growth and development of various cells under normal physiological conditions. The development of H2O2 sensors has received great research interest because of the importance of H2O2 in biological systems and its practical applications in other fields. In this study, a H2O2 electrochemical sensor was constructed based on chalcogenide molybdenum disulfide–gold–silver nanocomposite (MoS2-Au-Ag). Transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and energy dispersive spectroscopy (EDS) were utilized to characterize the nanocomposites, and the electrochemical performances of the obtained sensor were assessed by two electrochemical detection methods: cyclic voltammetry and chronoamperometry. The results showed that the MoS2-Au-Ag-modified glassy carbon electrode (GCE) has higher sensitivity (405.24 µA mM−1 cm−2), wider linear detection range (0.05–20 mM) and satisfactory repeatability and stability. Moreover, the prepared sensor was able to detect the H2O2 discharge from living tumor cells. Therefore, this study offers a platform for the early diagnosis of cancer and other applications in the fields of biology and biomedicine. Full article
(This article belongs to the Special Issue Synthesis and Sensor Applications of Hybrid Bionanomaterials)
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