Synthesis of Novel Anticancer Agents, Antivirals and Small Biological Molecules
A special issue of Symmetry (ISSN 2073-8994). This special issue belongs to the section "Chemistry: Symmetry/Asymmetry".
Deadline for manuscript submissions: closed (31 August 2021) | Viewed by 3175
Special Issue Editor
2. Department of Chemistry, University of South Florida, 4202 E. Fowler Ave., Tampa, FL 33620, USA
Interests: anticancer agents; antivirals; Parkinson’s disease; organic synthesis; drug design
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The global development of cancer registries has led to the discovery of novel drugs that derived from various sources that are used to treat several maladies including cancers and many viral diseases. About 80% of the world’s population depends on traditional therapeutics for several diseases, including anticancer and antiviral treatments. Many of these are symmetrical therapeutics (e.g., macrolides). The grouping together of antivirals, anticancer agents, and other small biological molecules from various sources in one review is not a matter of expediency, but follows from the increasing realization of the importance of the location as the most likely source of future “leads” in both areas. The currently available cancer and antiviral therapies still have various limitations, such as multi-drug resistance, undesired off-target effects, and unpredictable efficacies. The development of novel anticancer antiviral agents and other small biological molecules continues to be imperative to combat these diseases. The emerging molecular targets and signal pathways enable the development of novel strategies for the rational design of new anticancer agents, antiviral agents, and other small biologics. Numerous well-established synthetic methods and biological screening assays have paved the way for the discovery and development of new agents. Despite the availability of drugs in each area, more effective formulations are required. Some of these new drugs will undoubtedly come from natural products screening, in combination with synthetic modification, analog production, and combinatorial chemistry. In addition, the synthesis of other small biological molecules with specific disease targets are also welcome in this Special Issue of Symmetry. Both original research and review articles focusing on the rational design, synthesis, and/or biological evaluation of various anticancer and antiviral agents (including small molecules) as potential therapeutics are welcome to be submitted for publication in this Special Issue.
Prof. Dr. Ralph Salvatore
Guest Editor
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Keywords
- anticancer agents
- antiviral agents
- drug design
- synthesis
- small biologics
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