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Technologies
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Electrospinning Technologies for Biomedical and Biotechnological Applications
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Electrospinning Technologies for Biomedical and Biotechnological Applications

A special issue of Technologies (ISSN 2227-7080). This special issue belongs to the section "Innovations in Materials Processing".

Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 12570

Special Issue Editor

Dr. Yury A. Skorik

E-Mail Website1 Website2
Guest Editor
1. Head of the Laboratory of Natural Polymers, Institute of Macromolecular Compounds of the Russian Academy of Sciences, St. Petersburg, Russia
2. Head of the Analytical Chemistry Department, Almazov National Medical Research Centre, St. Petersburg, Russia
Interests: polysaccharides; biomaterials; tissue engineering; drug delivery; gene delivery; nanomedicine; nanocomposites; electrospinning
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The Special Issue “Electrospinning Technologies for Biomedical and Biotechnological Applications” is motived by the observed growing interests in the design, fabrication, and application of electrospun nanofiber materials in biomedical and biotechnological fields. It aims to provide broad coverage of the research progress, as well as up-to-date reviews addressing the various fundamental and applied problems of using electrospinning techniques for multiple bio-applications.

In this Special Issue, we seek contributions from active experts discussing the improvements in electrospinning technologies, and innovations in electrospun biomaterials, including applications in tissue engineering, regenerative medicine, wound healing, drug and gene delivery, filtration, and enzyme supports, among others. We intend that the Special Issue will provide a unique platform for the diffusion of new concepts and bio-applications of electrospun nonwoven materials, so as to continue the motivation and inspiration for further research in this newly invigorated field.

Dr. Yury A. Skorik
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Technologies is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrospinning
  • non-wovens
  • nanomaterials
  • tissue engineering
  • regenerative medicine
  • drug delivery
  • gene delivery
  • wound healing
  • filtration
  • enzyme immobilization

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Related Special Issue

Published Papers (3 papers)

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Research

9 pages, 4046 KiB  
Communication
Electrospun VDF-TeFE Scaffolds Modified by Copper and Titanium in Magnetron Plasma and Their Antibacterial Activity against MRSA
by Arsalan D. Badaraev, Marat I. Lerner, Dmitrii V. Sidelev, Evgeny N. Bolbasov and Sergei I. Tverdokhlebov
Technologies 2021, 9(1), 5; https://doi.org/10.3390/technologies9010005 - 6 Jan 2021
Cited by 4 | Viewed by 2590
Abstract
Copolymer solution of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) was used for electrospinning of fluoropolymer scaffolds. Magnetron co-sputtering of titanium and copper targets in the argon atmosphere was used for VDF-TeFE scaffolds modification. Scanning electron microscopy (SEM) showed that scaffolds have a nonwoven structure [...] Read more.
Copolymer solution of vinylidene fluoride with tetrafluoroethylene (VDF-TeFE) was used for electrospinning of fluoropolymer scaffolds. Magnetron co-sputtering of titanium and copper targets in the argon atmosphere was used for VDF-TeFE scaffolds modification. Scanning electron microscopy (SEM) showed that scaffolds have a nonwoven structure with mean fiber diameter 0.77 ± 0.40 μm, mean porosity 58 ± 7%. The wetting angle of the original (unmodified) hydrophobic fluoropolymer scaffold after modification by titanium begins to possess hydrophilic properties. VDF-TeFE scaffold modification by titanium/copper leads to the appearance of strong antibacterial properties. The obtained fluoropolymer samples can be successfully used in tissue engineering. Full article
(This article belongs to the Special Issue Electrospinning Technologies for Biomedical and Biotechnological Applications)
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13 pages, 4596 KiB  
Article
Electrosprayed Nanoparticles Based on Hyaluronic Acid: Preparation and Characterization
by Petr Snetkov, Kseniia Zakharova, Svetlana Morozkina, Mikhail Baranov, Roman Olekhnovich and Mayya Uspenskaya
Technologies 2020, 8(4), 71; https://doi.org/10.3390/technologies8040071 - 27 Nov 2020
Cited by 5 | Viewed by 3554
Abstract
Modern drug delivery systems demand the development of targeted polymer-carriers with the set of obligatory requirements. Thus, such capsules must have total biocompatibility, biodegradability, and possess non-allergenic, and non-tumorigenic properties. Hyaluronic acid (HA), as a natural linear polysaccharide that is included in the [...] Read more.
Modern drug delivery systems demand the development of targeted polymer-carriers with the set of obligatory requirements. Thus, such capsules must have total biocompatibility, biodegradability, and possess non-allergenic, and non-tumorigenic properties. Hyaluronic acid (HA), as a natural linear polysaccharide that is included in the pericellular and extracellular matrixes, satisfies all these demands in the best possible way. In this study, the biopolymer nanoparticles with an average diameter of 300 nm were successfully obtained from aqueous HA solutions by electrospraying technique and characterized. Due to the presence of active functional groups in the structure of HA, such polymer particles can incorporate various pharmaceutical agents. This finding expands the investigation and subsequent application of drug-loaded nanoparticles based on HA as challenging and advanced targeted delivery systems. Full article
(This article belongs to the Special Issue Electrospinning Technologies for Biomedical and Biotechnological Applications)
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9 pages, 1734 KiB  
Communication
Needleless Electrospinning of a Chitosan Lactate Aqueous Solution: Influence of Solution Composition and Spinning Parameters
by Daria N. Poshina, Igor A. Khadyko, Arina A. Sukhova, Ilya V. Serov, Natalia M. Zabivalova and Yury A. Skorik
Technologies 2020, 8(1), 2; https://doi.org/10.3390/technologies8010002 - 19 Dec 2019
Cited by 5 | Viewed by 5400
Abstract
The biological activity of chitosan determines its broad application as a biopolymer for non-woven wound dressings fabricated by electrospinning. The electrospinning process is affected by a large number of different factors that complicate its optimization. In the present work, the electrospinning of chitosan [...] Read more.
The biological activity of chitosan determines its broad application as a biopolymer for non-woven wound dressings fabricated by electrospinning. The electrospinning process is affected by a large number of different factors that complicate its optimization. In the present work, the electrospinning of chitosan lactate was carried out using a needleless technique from water solutions of different compositions. Surface response methodology was used to evaluate the effects of the concentration of chitosan, polyethylene oxide, and ethanol on solution properties, such as viscosity, surface tension, and conductivity, as well as the process characteristics and fiber quality. The viscosity of the spinning solution is determined by the polymer concentration as well as by the interpolymer interactions. The addition of ethanol to the spinning solutions effectively decreases the solution surface tension and conductivity, while increasing the volatility of the solvent, to provide more intense fiber spinning. Atomic force microscopy revealed that the chitosan lactate fibers were obtained without defects and with a narrow thickness distribution. The spinning parameters, voltage, distance between electrodes, and rotation speed of the spinning electrode had insignificant influences on the fiber diameter during needleless electrospinning. Full article
(This article belongs to the Special Issue Electrospinning Technologies for Biomedical and Biotechnological Applications)
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