Exploring the Multifaceted Role of Antioxidants: From Molecular Mechanisms to Therapeutic Applications
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Novel Methods in Toxicology Research".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 1345
Special Issue Editors
Interests: medicinal chemistry; drug mechanism; novel anti-inflammatory and antibacterial drugs; novel drug preparations; pharmacology; toxicology.
Interests: metabolic liver disease; utilization and development of flavonoids; pharmacology; toxicology
Special Issue Information
Dear Colleagues,
Antioxidants are crucial substances that inhibit or decelerate the oxidation of other molecules. They work by scavenging free radicals, inhibiting oxidation reactions, and disrupting oxidative chain reactions. Both endogenous metabolic processes and exogenous environmental factors generate free radicals and reactive oxygen species (ROS). While controlled concentrations of ROS play vital physiological roles, their excessive accumulation causes oxidative stress, damaging cells and tissues and leading to various pathological conditions.
Investigating antioxidants is crucial as they mitigate oxidative stress, suppress inflammation, preserve mitochondrial function, modulate cellular signaling pathways, fortify the immune system, and enhance toxin metabolism and excretion. Understanding antioxidant mechanisms and their protective effects could lead to their application in disease prevention, treatment, oxidative stress mitigation, and a reduction in the impact of environmental toxins. These advancements span biochemistry, molecular biology, pharmacology, environmental science, and clinical medicine.
This Special Issue will explore the protective role of antioxidants against toxicity across diverse biological models, including human-oriented models, plants, invertebrates, vertebrates, and cell lines. By encompassing various experimental systems and promoting interdisciplinary research, we aim to highlight cutting-edge research and novel insights. Our aim is to provide a comprehensive understanding of antioxidant mechanisms, their interactions with biological systems, and their potential therapeutic applications.
We welcome submissions that explore the multifaceted role of antioxidants, from molecular mechanisms to clinical and environmental applications, fostering collaboration between scientific disciplines to improve health and mitigate oxidative stress and environmental toxins.
Prof. Dr. Jianyong Li
Dr. Meizhou Huang
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- enzymatic antioxidants
- non-enzymatic antioxidants
- reactive oxygen species
- inflammation response
- oxidative stress
- energy metabolism
- toxicity
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