Measure to Improve Vaccination Coverage In at Risk Categories: Pregnant Women, Healthcare Workers and Patients with Chronic Diseases—Second Edition

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Clinical Immunology".

Deadline for manuscript submissions: closed (15 September 2024) | Viewed by 4223

Special Issue Editors


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Guest Editor
Department of Biomedical Sciences and Morphological and Functional Images (BIOMORF), University of Messina, 98124 Messina, Italy
Interests: communicable diseases and vaccination strategies; risk communication; non-communicable disease; public health; HCAIs
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Guest Editor
Department of Biomedical Sciences, Dental Sciences and Morpho-Functional Images, University of Messina, 98125 Messina, Italy
Interests: vaccination coverage; vaccination strategies; healthcare-associated infections; hospital hygiene; flu
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Guest Editor
1. Department of Health Promotion, Maternal and Child Care, Internal Medicine and Excellence Specialties, University of Palermo, 90127 Palermo, Italy
2. Vaccination Unit, University Hospital of Palermo, Palermo, Italy
Interests: vaccination; vaccines; vaccine hesitancy; vaccine outreach; vaccine communication; paediatric vaccination; adolescent vaccination; adult vaccination; elderly vaccination
Special Issues, Collections and Topics in MDPI journals
Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, PV, Italy
Interests: public health; epidemiology; prevention; vaccines; immunisation policies; information and communication technology, digital health
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, a phenomenon known as "vaccine hesitancy" has spread throughout the world, even among healthcare workers, determining a reduction in vaccination coverage, although vaccination is widely considered to be an efficacious and cost-effective health technology.

Although some data about vaccination coverage are not systematically available for some at-risk categories, i.e., pregnant women, healthcare workers, and patients with chronic diseases, the international literature shows a poor adhesion.

Manuscripts reporting on vaccines administered to pregnant women, at-risk patients (with chronic diseases such as, i.e., HIV or kidney failure, or other risk factors), and healthcare workers and on strategies adopted to promote vaccination adherence by these categories are welcomed for this Special Issue.

This Special Issue encourages the submission of original articles, systematic reviews, meta-analyses, short communications, and other types of articles that describe measures and strategies to improve vaccination coverage in these categories that could be adapted in other settings and countries.

Dr. Cristina Genovese
Dr. Squeri Raffaele
Dr. Claudio Costantino
Dr. Anna Odone
Guest Editors

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Keywords

  • vaccination coverage
  • improvement
  • at-risk populations
  • pregnancy
  • healthcare workers

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Published Papers (2 papers)

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Research

10 pages, 251 KiB  
Article
Vaccination and Trust in the National Health System among HIV+ Patients: An Italian Cross-Sectional Survey
by Fabrizio Bert, Antonino Russotto, Alex Pivi, Benedetta Mollero, Gianluca Voglino, Giancarlo Orofino and Roberta Siliquini
Vaccines 2023, 11(8), 1315; https://doi.org/10.3390/vaccines11081315 - 2 Aug 2023
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Abstract
Background: This study aimed to evaluate the knowledge, attitudes, and practises (KAP) of individuals living with HIV (PLWH) regarding vaccines and their trust in the Italian national health system (NHS). Methods: A cross-sectional survey was conducted at Amedeo di Savoia Hospital in Turin, [...] Read more.
Background: This study aimed to evaluate the knowledge, attitudes, and practises (KAP) of individuals living with HIV (PLWH) regarding vaccines and their trust in the Italian national health system (NHS). Methods: A cross-sectional survey was conducted at Amedeo di Savoia Hospital in Turin, Italy, involving 160 HIV-positive patients. Descriptive statistics were utilised to analyse variables such as vaccination status and intention, perceived risk of infection, and disease severity. The infections were categorised into sexually transmitted diseases and other vaccine-preventable diseases. Results: Except for the perceived severity of infection, there were no significant differences in the percentages between the two infection groups for the variables examined. Concerning patients’ perception of the Italian NHS, a high percentage of the sample believed in the information provided by healthcare workers (HCWs) (95.6%) and considered HCWs up-to-date on vaccines (93.1%). However, a considerable proportion expressed concerns about insufficient information on vaccine risks from HCWs (33.3%), perceived judgement by HCWs for vaccine refusal (40.3%), and suspected financial interests of HCWs in vaccination (19.5%). Conclusions: Some HIV+ patients may hesitate to be vaccinated or hold misconceptions about the severity of certain infectious diseases. Additionally, there are concerns about trust in the Italian NHS and communication by HCWs. Full article
10 pages, 277 KiB  
Article
Safety of Rotavirus Vaccination in Preterm Infants Admitted in Neonatal Intensive Care Units in Sicily, Italy: A Multicenter Observational Study
by Claudio Costantino, Arianna Conforto, Nicole Bonaccorso, Livia Cimino, Martina Sciortino, Mario Palermo, Kim Maiolo, Lucia Gabriella Tina, Pasqua Maria Betta, Mariacarmela Caracciolo, Carmine Mattia Loretta, Alessandro Arco, Eloisa Gitto, Salvino Marcello Vitaliti, Domenica Mancuso, Giuliana Vitaliti, Vincenzo Rosella, Giuseppa Pinello, Giovanni Corsello, Gregorio Serra, Bruna Gabriele, Fabio Tramuto, Vincenzo Restivo, Emanuele Amodio and Francesco Vitaleadd Show full author list remove Hide full author list
Vaccines 2023, 11(4), 718; https://doi.org/10.3390/vaccines11040718 - 23 Mar 2023
Cited by 5 | Viewed by 2057
Abstract
Rotavirus (RV) is among the most common vaccine-preventable diseases in children under five years of age. Despite the severity of rotavirus pathology in early childhood, rotavirus vaccination for children admitted to the neonatal intensive care unit (NICU), who are often born preterm and [...] Read more.
Rotavirus (RV) is among the most common vaccine-preventable diseases in children under five years of age. Despite the severity of rotavirus pathology in early childhood, rotavirus vaccination for children admitted to the neonatal intensive care unit (NICU), who are often born preterm and with various previous illnesses, is not performed. This multicenter, 3-year project aims to evaluate the safety of RV vaccine administration within the six main neonatal intensive care units of the Sicilian Region to preterm infants. Methods: Monovalent live attenuated anti-RV vaccination (RV1) was administered from April 2018 to December 2019 to preterm infants with gestational age ≥ 28 weeks. Vaccine administrations were performed in both inpatient and outpatient hospital settings as a post-discharge follow-up (NICU setting) starting at 6 weeks of age according to the official immunization schedule. Any adverse events (expected, unexpected, and serious) were monitored from vaccine administration up to 14 days (first assessment) and 28 days (second assessment) after each of the two scheduled vaccine doses. Results: At the end of December 2019, 449 preterm infants were vaccinated with both doses of rotavirus vaccine within the six participating Sicilian NICUs. Mean gestational age in weeks was 33.1 (±3.8 SD) and the first dose of RV vaccine was administered at 55 days (±12.9 SD) on average. The mean weight at the first dose was 3388 (SD ± 903) grams. Only 0.6% and 0.2% of infants reported abdominal colic and fever above 38.5 °C in the 14 days after the first dose, respectively. Overall, 1.9% EAEs were observed at 14 days and 0.4% at 28 days after the first/second dose administration. Conclusions: Data obtained from this study confirm the safety of the monovalent rotavirus vaccine even in preterm infants with gestational age ≥ 28 weeks, presenting an opportunity to improve the vaccination offer both in Sicily and in Italy by protecting the most fragile infants who are more at risk of contracting severe rotavirus gastroenteritis and nosocomial RV infection. Full article
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