Therapeutic Vaccination of HIV-Infected Patients 2.0
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "HIV Vaccines".
Deadline for manuscript submissions: closed (30 May 2021) | Viewed by 10225
Special Issue Editors
Interests: emerging infectious diseases (SARS-CoV-2, HIV-1, fungi, bacteria); dendritic cells; adaptive immunity
Special Issues, Collections and Topics in MDPI journals
Interests: 3D cell culture and pathogen interactions (fungi, HIV-1, SARS-CoV-2); lung model; mucosa; T zell zone model; innate immunity; dendritic cells; T cell polarization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In 2019, 38 million people worldwide were living with human immunodeficiency virus 1 (HIV-1), 1.7 million new infections were reported, and almost 1 million patients died of AIDS. Anti-retroviral treatment (ART) can dramatically extend the lives of HIV-1-infected individuals and, according to the UNAIDS 2019 fact sheet, 25.4 million HIV-1-infected individuals are currently receiving ART therapy. A fast track strategy to end the AIDS epidemic by 2030 was postulated by the organization UNAIDS. To reach this visionary aim, rapid progress has to be made in the development of HIV prevention strategies and improved treatment options. If progress is too slow, as it looks like right now, the UNAIDS-commissioned modelling predicts a rebound pandemic by 2030, with an even more serious threat to future health. The increasing trend of resistance to widely used antiretroviral drugs in HIV-1-infected patients urges the development of safe and efficient vaccines, as well as anti-retroviral therapies, that are affordable and easy to administer. Despite the efforts of numerous research teams all around the world, no effective HIV-1 vaccine is available to date. The extremely high genetic variability of the virus and its ability to suppress protective immune responses hinder the development of a vaccine based on conventional methodologies. Another obstacle is the lack of adequate laboratory models to test potential vaccines on human tissue in a high-throughput manner.
In line with these considerations, we would like to encourage the submission of works on the recent advances in the development of novel therapeutic vaccines for the treatment of HIV to this Special Issue. Studies using vaccine immunotherapy, adoptive cell transfer, CAR-T cells, HIV-associated and HIV-specific antigen stimulation of immune/antigen-presenting cells, and the use of nucleic acid transfer are welcome. Adding new information about these subjects may improve the design and the efficiency of new therapeutic vaccination strategies of HIV.
Dr. Wilfried Posch
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- therapeutic vaccines
- immunotherapy
- cell-based vaccination
- adoptive cells transfer
- CAR-T cells
- HIV-1
- AIDS
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
