Viruses Associated with Gastroenteritis
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Human Virology and Viral Diseases".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 96
Special Issue Editors
Interests: rotavirus; hepatitis D virus; hepatitis B virus; virus–host interactions
Interests: rotavirus; norovirus; viruses causing gastroenteritis; African swine fever virus; vaccine development; molecular epidemiology
Special Issue Information
Dear Colleagues,
It is estimated that 50-70% of all cases of infectious acute gastroenteritis (AGE) worldwide are caused by viruses. Noroviruses, rotaviruses, adenoviruses and astroviruses are the main causative agents, accounting for 3-5 billion cases and 1.5 million deaths per year; these particularly affect children in low and middle-income countries (LMIC) with poor access to safe water, sanitation and health care infrastructure.
Prevention and vaccination remain the sole means of reducing the incidence of this disease. As of today, the only approved vaccines target rotaviruses, and these are included in infant vaccination plans in many countries, contributing to a reduction in the number of new infections and cases of severe diarrhea. However, these vaccines seem to show reduced efficacy in LMICs. Several factors might contribute to this phenomenon, including host genetic factors (e.g., histo-blood group antigens (HBGAs)), the gut microbiota and environmental enteropathy. Several vaccine candidates that target noroviruses are also being tested in clinical trials at different stages.
Rotaviruses, noroviruses and astroviruses have RNA genomes with significantly higher rates of mutation when compared to DNA viruses, including adenoviruses. Therefore, the implementation of monitoring plans that aim to control circulating strains and variants is crucial to ensuring the accuracy of laboratory diagnosis.
This Special Issue will focus on the mechanisms implicated in the pathogenesis of viruses associated with acute gastroenteritis, with an emphasis on their pathophysiology, virus tropism and replication, vaccine design and production, preventive measures, the development of new therapeutic approaches, the immune response, differential laboratory diagnosis, the role of the microbiota, host genetic factors, molecular epidemiology, and surveillance.
Dr. Celso Cunha
Dr. Claudia Istrate
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- vaccines
- therapeutic approaches
- virus replication
- molecular epidemiology
- immune response
- microbiome
- diagnosis
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
