Human Leukocyte Antigen (HLA) in Viral Infections
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 80
Special Issue Editor
Interests: human leukocyte antigen; T and B cell receptor sequencing; adaptive immune system; immunometabolism; immune responses to vaccination and viral infections
Special Issue Information
Dear Colleagues,
Human Leukocyte Antigens (HLAs) play a pivotal role in the immune response to viral infections. These molecules present pathogen-derived peptides to T cells, initiating adaptive immunity. Variations in HLA gene alleles and their expression patterns can significantly influence the outcome of viral infections, from viral persistence and immune evasion to the clearance of infection. Understanding the intricate interplay between HLA polymorphism and viral pathogenesis is crucial for developing effective antiviral therapies and vaccines. This Special Issue highlights cutting-edge research exploring the multifaceted role of HLAs in viral infections. We invite submissions encompassing diverse areas, including HLA-mediated viral control, viral immune evasion strategies targeting HLAs, the impact of HLA diversity on viral evolution, and the implications of HLA associations for antiviral drug and vaccine design. This Special Issue will provide a comprehensive overview of the field's current state and identify key areas for future investigation, ultimately contributing to developing novel strategies to combat viral diseases.
Dr. Nicholas Borcherding
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- HLA
- viral infection
- immune response
- T cells
- antigen presentation
- viral evasion
- immunogenetics
- polymorphism
- disease susceptibility
- vaccine development
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