SARS-CoV-2 Neutralizing Antibodies 3rd Edition
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Coronaviruses".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 84
Special Issue Editor
Special Issue Information
Dear Colleagues,
At the end of 2019, SARS-CoV-2 was discovered and quickly spread around the world, posing a severe threat to global public health systems. The pandemic resulted in more than 765 million confirmed cases and nearly 7 million associated deaths. Although WHO declared COVID-19 to no longer be a global health emergency on 5 May 2023, the undeniable truth is that the disease is “here to stay” due to its continued evolution. We have witnessed the successful development of a series of vaccines, monoclonal antibodies, highly concentrated immunoglobulin, and convalescent plasma for preventative and therapeutic use during the past 4 years. The neutralizing antibodies in those products play an important role. Although a correlation between neutralizing antibodies and protection has not yet been determined, it is generally believed that the higher the titer of neutralizing antibodies, the better the efficacy. Thus, it is important to identify the correlation between neutralizing antibodies and efficacy. Moreover, different neutralization assays used in different laboratories are variable, and results from different laboratories on neutralizing antibodies may not be comparable. Thus, research concerning standardized neutralizing assays and standards around neutralizing antibodies against SARS-CoV-2 and its variants is still needed.
In this Special Issue, we continue to focus on neutralization assays, assay validation, detection procedures, neutralizing antibody standards and references, as well as the antibody immune response induced by vaccines and the hybrid immunity. We seek contributions featuring original research and review articles, as well as short communications, on this topic.
Prof. Dr. Youchun Wang
Guest Editor
Manuscript Submission Information
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Keywords
- SARS-CoV-2
- neutralizing antibodies
- neutralization assays
- standards
- monoclonal antibodies
- vaccines
- viral variants
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