HIV Protease
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 211
Special Issue Editor
Interests: spin-labeling; electron paramagnetic resonance (EPR); molecular motion; conformational sampling; HIV-1 protease; drug-pressure selected mutations; natural polymorphisms
Special Issue Information
Dear Colleagues,
HIV-1 protease remains a target for the treatment of those living with HIV-1 infection. Until vaccines are developed, and latent infections can be overcome, the continued development of novel inhibitors and research into the mechanism of maturation and co-evolution of HIV-1 protease are essential for the management of viral loads and prevention of maturation of infectious virus particles. Research papers, perspectives, and review articles exploring/summarizing the development of novel inhibitors, drug resistance inhibitor development, multifunctional inhibitors, structural and dynamic studies, co-evolution of protease with other viral proteins, and comparative studies of resistance mechanisms from various subtypes are invited to contribute to this Special Issue.
Prof. Dr. Gail E. Fanucci
Guest Editor
Manuscript Submission Information
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Keywords
- HIV protease
- antiretroviral therapy
- drug resistance
- inhibitor development
- viral maturation
- viral co-evolution
- natural polymorphism
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