Lactococcosis: A Single Disease for Multiple Lactococcus Species

A special issue of Animals (ISSN 2076-2615).

Deadline for manuscript submissions: 25 February 2025 | Viewed by 773

Special Issue Editors


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Guest Editor
Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Italy
Interests: genetics and genomics; genetic resistance to animal diseases; fish diseases; antibiotic resistance; molecular characterization of bacteria; invasive alien species
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Guest Editor
Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e Valle d’Aosta, Italy
Interests: aquaculture; fish biology; aquatic organisms pathology; antibiotic resistance; conservation of biodiversity in aquatic environments; alien invasive species
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
PHARMAQ Analytiq UK Ltd., Inverness, UK
Interests: emerging infectious diseases; molecular diagnostics; vaccinology; immuno-proteomics; aquaculture; eDNA; microbial genomics in aquatic species; fish and shellfish diseases and aquatic pathology

Special Issue Information

Dear Colleagues,

Lactococcosis is an emergent bacterial infection affecting a wide range of host species. It represents one of the main issues facing freshwater and marine fish. Moreover, this disease can affect several terrestrial animals, including humans. Due to its broad host range and potential impact on both animal populations and human health, lactococcosis is of notable concern from a One Health perspective. Only recently was Lactococcus garvieae reported as not being the only agent for this disease. L. petauri and L. formosensis have now also been described, as causal agents of lactococcosis.

These discoveries highlight this disease’s complexity and underscore the need for comprehensive research to understand its epidemiology, pathogenesis, and control.

We invite original contributions that focus on the following topics:

  • Diagnostic methods for identifying lactococcosis pathogens.
  • Biochemical and molecular characterisation of lactococcosis pathogens.
  • Virulence factors of lactococcosis pathogens.
  • Antimicrobial resistance in lactococcosis pathogens.
  • Host vaccinology in lactococcosis-affected organisms.
  • Immunology studies of infected hosts.
  • Genetic and genomic resistance in hosts.
  • Development of new treatments and therapies for lactococcosis.
  • Epidemiology of lactococcosis.
  • Animal models for studying lactococcosis.
  • Strategies for the prevention and control of lactococcosis.
  • Economic and health impacts of lactococcosis.
  • Technological innovations in the diagnosis and treatment of lactococcosis.
  • Clinical case studies related to lactococcosis.
  • Analysis of host-pathogen interactions in lactococcosis.

This Special Issue aims to deepen our understanding of lactococcosis and to inform the development of effective management and control strategies.

Dr. Silvia Colussi
Dr. Giuseppe Esposito
Dr. Khalid Shahin
Guest Editors

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Keywords

  • lactococcosis
  • fish diseases
  • antimicrobial resistance
  • host–pathogen interactions
  • epidemiology
  • diagnostic methods

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Published Papers (1 paper)

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Research

15 pages, 2706 KiB  
Article
First Detection of Lactococcus petauri in Domestic Dogs in Italy
by Simona Sciuto, Giuseppe Esposito, Paolo Pastorino, Khalid Shahin, Katia Varello, Eliana Trabunella, Giulia Milanese, Sonia Scala, Marino Prearo, Pier Luigi Acutis, Angelo Salerno, Simona Zoppi and Silvia Colussi
Animals 2024, 14(22), 3279; https://doi.org/10.3390/ani14223279 - 14 Nov 2024
Viewed by 444
Abstract
Lactococcus garvieae has been considered for a long time the only causal agent of lactococcosis. In recent years, different papers reported the involvement of other two bacterial species: Lactococcus petauri and Lactococcus formosensis. A different host tropism has been described for these [...] Read more.
Lactococcus garvieae has been considered for a long time the only causal agent of lactococcosis. In recent years, different papers reported the involvement of other two bacterial species: Lactococcus petauri and Lactococcus formosensis. A different host tropism has been described for these species where L. garvieae and L. petauri are predominant species in fish and humans’ infections, while L. formosensis in bovine. L. garvieae has been reported as rare infectious agent in dog. This paper represents the first isolation of L. petauri in two domesticated dog cases from urine and skin samples, respectively. The recovered L. petauri has been identified using PCR and sequencing based on Internal Transcribe Spacer (ITS) and phylogenetic analysis showed that it belongs to the L. petauri cluster with a 100% of identity with sequences previously reported from fish isolates while there were differences with L. petauri isolated from urinary tract infection from humans. L. petauri in human infection has been considered not necessarily deriving from the ingestion of contaminated food but rather as an opportunistic pathogen colonization intestinal tract. Differences among virulotypes have been reported for humans and dogs, and a comparison was also made between the virulotyping of L. petauri and L. garvieae in dogs. The antimicrobial pattern showed susceptibility for the election treatment molecules. These data contribute to our understanding of the host trophism of this species which was misclassified for long time and provide new data on its virulence factors and antimicrobial resistance. Full article
(This article belongs to the Special Issue Lactococcosis: A Single Disease for Multiple Lactococcus Species)
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