Advances in Mammary Gland Biology and Lactation of Ruminants: Second Edition

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Small Ruminants".

Deadline for manuscript submissions: 16 December 2024 | Viewed by 1200

Special Issue Editor


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Guest Editor
School of Agriculture and Environment, Massey University, Private Bag 11222, Palmerston North 4442, New Zealand
Interests: sheep dairy; lactation in sheep; developmental programming; fetal development; mastitis in sheep and beef cattle
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Dear Colleagues,

Apart from its milk-producing function, the mammary gland is a unique mammalian organ in two major ways. First, it is almost invariably sited outside of the body cavity, and second, it grows and regresses several times during the animal’s life. Being isolated from the body helps to protect the body from infections that are common in the mammary gland due to the suitability of the intramammary environment for microorganisms, and the gland has both local and systemic methods of protection to combat mastitis. Being isolated also facilitates the growth and regression of the gland by separating the many growth factors that are involved from other body organs (where they might cause chaos). Add to these functions the mechanism by which the gland produces colostrum to provide offspring with immunological competence as well as with milk, both of which are produced in amounts and compositions that are appropriate for the species and the offspring. This surely indicates that the mammary gland is one of the most complicated and fascinating organs.

It has been seven years since Michael Akers wrote the 100-year review on mammary development and lactation, in which he pointed out that despite great advances in knowledge, the fundamental questions regarding mammary development and lactation have changed little. The more we discover, the more questions are raised, and this has resulted in many groups studying a wide variety of lactation-related topics. If we also consider the many different types of dairy animals and production systems being studied, there is a huge amount of research happening in relation to mammary biology. Thus, the plan for this Special Issue is to highlight research in mammary biology and lactation in ruminants.

Considering the success of our previous Special Issue, we are pleased to launch “Advances in Mammary Gland Biology and Lactation of Ruminants: Second Edition”. We welcome the submission of research articles and literature reviews.

Dr. Sam Peterson
Guest Editor

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Keywords

  • mammary biology
  • mammogenesis
  • lactogenesis
  • galactopoiesis
  • mastitis
  • mammary histopathology
  • endocrine signals
  • epigenetic effects
  • lactational physiology
  • milk removal
  • colostrum
  • somatic cells
  • milk conductivity
  • mammary metabolism

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Research

20 pages, 2399 KiB  
Article
The Use of Machine Learning to Predict Prevalence of Subclinical Mastitis in Dairy Sheep Farms
by Yiannis Kiouvrekis, Natalia G. C. Vasileiou, Eleni I. Katsarou, Daphne T. Lianou, Charalambia K. Michael, Sotiris Zikas, Angeliki I. Katsafadou, Maria V. Bourganou, Dimitra V. Liagka, Dimitris C. Chatzopoulos and George C. Fthenakis
Animals 2024, 14(16), 2295; https://doi.org/10.3390/ani14162295 - 6 Aug 2024
Cited by 1 | Viewed by 992
Abstract
The objective of the study was to develop a computational model with which predictions regarding the level of prevalence of mastitis in dairy sheep farms could be performed. Data for the construction of the model were obtained from a large Greece-wide field study [...] Read more.
The objective of the study was to develop a computational model with which predictions regarding the level of prevalence of mastitis in dairy sheep farms could be performed. Data for the construction of the model were obtained from a large Greece-wide field study with 111 farms. Unsupervised learning methodology was applied for clustering data into two clusters based on 18 variables (17 independent variables related to health management practices applied in farms, climatological data at the locations of the farms, and the level of prevalence of subclinical mastitis as the target value). The K-means tool showed the highest significance for the classification of farms into two clusters for the construction of the computational model: median (interquartile range) prevalence of subclinical mastitis among farms was 20.0% (interquartile range: 15.8%) and 30.0% (16.0%) (p = 0.002). Supervised learning tools were subsequently used to predict the level of prevalence of the infection: decision trees, k-NN, neural networks, and Support vector machines. For each of these, combinations of hyperparameters were employed; 83 models were produced, and 4150 assessments were made in total. A computational model obtained by means of Support vector machines (kernel: ‘linear’, regularization parameter C = 3) was selected. Thereafter, the model was assessed through the results of the prevalence of subclinical mastitis in 373 records from sheep flocks unrelated to the ones employed for the selection of the model; the model was used for evaluation of the correct classification of the data in each of 373 sets, each of which included a test (prediction) subset with one record that referred to the farm under assessment. The median prevalence of the infection in farms classified by the model in each of the two categories was 10.4% (5.5%) and 36.3% (9.7%) (p < 0.0001). The overall accuracy of the model for the results presented by the K-means tool was 94.1%; for the estimation of the level of prevalence (<25.0%/≥25.0%) in the farms, it was 96.3%. The findings of this study indicate that machine learning algorithms can be usefully employed in predicting the level of subclinical mastitis in dairy sheep farms. This can facilitate setting up appropriate health management measures for interventions in the farms. Full article
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