Pathogenesis and Preventive Methods of Animal Multidrug-Resistant Bacterial Infections

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 1351

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Guest Editor
Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, USA
Interests: molecular epidemiology of antimicrobial resistance
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Special Issue Information

Dear Colleagues,

We would like to invite you to contribute a paper to be included in the Special Issue “Pathogenesis and Preventive Methods of Animal Multidrug-Resistant Bacterial Infections”. This Special Issue will focus on novel approaches to identify risk factors and pathogenesis mechanisms of MDR infections in animals with the goal of preventing them.  We aim to reduce the development and spread of MDR diseases between animals, humans, and the environment to enhance animal welfare and One Health. We hope that you accept this offer and help us build this Special Issue centered around infectious diseases, epidemiology, and prevention. Your valuable contribution will be deeply appreciated.

Dr. Laura Huber
Guest Editor

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Keywords

  • multidrug resistance
  • infectious diseases
  • One Health
  • veterinary preventative medicine

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Published Papers (1 paper)

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Research

8 pages, 246 KiB  
Article
Enteropathogenic and Multidrug-Resistant blaCTX-M-Carrying E. coli Isolates from Dogs and Cats
by Catherine Biondo Feitosa, Gabriel Siqueira dos Santos, Natalia Carrillo Gaeta, Gustavo da Silva Schiavi, Carla Gasparotto Chande Vasconcelos, Jonas Moraes Filho, Marcos Bryan Heinemann and Adriana Cortez
Animals 2024, 14(17), 2463; https://doi.org/10.3390/ani14172463 - 24 Aug 2024
Viewed by 1012
Abstract
Enteropathogenic Escherichia coli (EPEC) are pathogens associated with gastrointestinal illnesses. Dogs and cats can harbor EPEC, and antimicrobial resistance may impair necessary treatments. This study characterized E. coli strains from dogs and cats, focusing on phylogroup classification, virulence factors, and antimicrobial resistance profiles. [...] Read more.
Enteropathogenic Escherichia coli (EPEC) are pathogens associated with gastrointestinal illnesses. Dogs and cats can harbor EPEC, and antimicrobial resistance may impair necessary treatments. This study characterized E. coli strains from dogs and cats, focusing on phylogroup classification, virulence factors, and antimicrobial resistance profiles. Ninety-seven E. coli isolates from fecal samples of 31 dogs and 3 cats were obtained from a private diagnostic laboratory in Botucatu, Brazil, from March to October 2021. The antimicrobial susceptibility was assessed using the disk diffusion method. Polymerase chain reaction (PCR) was employed to screen for blaCTX-M and genes encoding virulence factors, as well as to classify the isolates into phylogroups. Twenty isolates were positive for intimin encoding gene eae and, consequently, these isolates were classified as EPEC (20.62%). Notably, 5.1% (5/97) of the isolates exhibited extended-spectrum β-lactamase (ESBL) production and 13.4% (13/97) were identified as multidrug-resistant bacteria. Phylogroups A and B2 were the most prevalent, comprising 29.9% (29/97) and 26.8% (26/97) of the bacterial isolates, respectively. This characterization highlights the prevalence of EPEC in domestic animals, emphasizing the potential risk they pose to public health and highlighting the urgency of responsible antimicrobial use in veterinary practices and the important role of laboratories in the surveillance of pathogenic multidrug-resistant bacteria. Full article
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