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Apicomplexan Parasites in Animals: Insights into Epidemiology, Control, Vaccination, and...
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Apicomplexan Parasites in Animals: Insights into Epidemiology, Control, Vaccination, and Host Interactions

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 947

Special Issue Editors

Dr. Mingming Liu

E-Mail Website
Guest Editor
1. School of Basic Medicine, Hubei University of Arts and Science, Xiangyang, China
2. National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan
Interests: Babesiosis; human parasitology; tick-borne diseases
Dr. Kun Li

E-Mail Website
Co-Guest Editor
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China
Interests: gut microbiota modification with a focus on the gut-disease relation
Special Issues, Collections and Topics in MDPI journals
Dr. Jixu Li

E-Mail Website
Co-Guest Editor
State Key Laboratory of Plateau Ecology and Agriculture, College of Agriculture and Animal Science, Qinghai University, Xining, China
Interests: Toxoplasma gondii; tick-borne diseases; animal parasitology

Special Issue Information

Dear Colleagues,

Apicomplexan parasites are significant pathogens affecting animals and are responsible for a range of serious diseases, such as Babesiosis, Cryptosporidiosis, and Toxoplasmosis. These diseases contribute substantially to deadly parasitic infections, yet effective vaccines and therapeutic options remain limited. This Special Issue aims to gather valuable insights that will support the development of novel strategies for controlling diseases caused by Apicomplexan parasites in animals.

This Special Issue aims to showcase recent advances in the following areas related to Apicomplexan parasites in animals: epidemiology, control measures, vaccination strategies, and host–parasite interactions; research contributions to Babesiosis, Cryptosporidiosis, Toxoplasmosis, and other Apicomplexan-related diseases are also highly encouraged. We aim to enhance understanding to combat these significant parasitic infections through collective research.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  1. Epidemiology in Apicomplexan parasites in animals.
  2. Screening novel drugs or repurposing existing drugs for the treatment of diseases caused by Apicomplexan parasites.
  3. Exploring new vaccine candidates against Apicomplexan parasites.
  4. Research involving host–pathogens relationships and biological mechanisms involved in the pathogenesis of Apicomplexan parasites.

We look forward to receiving your contributions.

Dr. Mingming Liu
Guest Editor

Dr. Kun Li
Dr. Jixu Li
Co-Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Apicomplexa
  • animals
  • epidemiology
  • control
  • vaccine
  • host interactions

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Published Papers (1 paper)

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Review

29 pages, 2588 KiB  
Review
Food and Waterborne Cryptosporidiosis from a One Health Perspective: A Comprehensive Review
by Munwar Ali, Yaru Ji, Chang Xu, Qazal Hina, Usama Javed and Kun Li
Animals 2024, 14(22), 3287; https://doi.org/10.3390/ani14223287 - 14 Nov 2024
Viewed by 694
Abstract
A sharp rise in the global population and improved lifestyles has led to questions about the quality of both food and water. Among protozoan parasites, Cryptosporidium is of great importance in this regard. Hence, Cryptosporidium’s associated risk factors, its unique characteristics compared [...] Read more.
A sharp rise in the global population and improved lifestyles has led to questions about the quality of both food and water. Among protozoan parasites, Cryptosporidium is of great importance in this regard. Hence, Cryptosporidium’s associated risk factors, its unique characteristics compared to other protozoan parasites, its zoonotic transmission, and associated economic losses in the public health and livestock sectors need to be focused on from a One Health perspective, including collaboration by experts from all three sectors. Cryptosporidium, being the fifth largest food threat, and the second largest cause of mortality in children under five years of age, is of great significance. The contamination of vegetables, fresh fruits, juices, unpasteurized raw milk, uncooked meat, and fish by Cryptosporidium oocysts occurs through infected food handlers, sewage-based contamination, agricultural effluents, infected animal manure being used as biofertilizer, etc., leading to severe foodborne outbreaks. The only Food and Drug Administration (FDA)-approved drug, Nitazoxanide (NTZ), provides inconsistent results in all groups of patients, and currently, there is no vaccine against it. The prime concerns of this review are to provide a deep insight into the Cryptosporidium’s global burden, associated water- and foodborne outbreaks, and some future perspectives in an attempt to effectively manage this protozoal disease. A thorough literature search was performed to organize the most relevant, latest, and quantified data, justifying the title. The estimation of its true burden, strategies to break the transmission pathways and life cycle of Cryptosporidium, and the search for vaccine targets through genome editing technology represent some future research perspectives. Full article
(This article belongs to the Special Issue Apicomplexan Parasites in Animals: Insights into Epidemiology, Control, Vaccination, and Host Interactions)
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