Evaluation of the Use of Antimicrobial Intravenous Limb Perfusion to Treat Septic Digital Lesions in Cattle: Why and How to Reduce the Use of These Drugs in Systemic and Local Therapy
A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Cattle".
Deadline for manuscript submissions: 12 February 2025 | Viewed by 2380
Special Issue Editors
Interests: equine surgery; farm animal surgery; equine emergency; laparoscopy; endoscopy
Interests: equine surgery; farm animal surgery; equine emergency; endoscopy; laparoscopy
Interests: farm animal surgery; digital dermatitis
Interests: equine surgery; equine laparoscopy; lameness; equine urogenital surgery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Deep digital septic conditions and soft tissue infections of the bovine foot, such as interdigital phlegmon, are responsible for severe lameness, a consequent decrease in milk production and possible premature culling. Antimicrobial intravenous regional limb perfusion (IVRLP) is a well-established technique for treating or preventing orthopedic infections of equine distal limbs. Several clinical studies have investigated its use for the treatment of digital septic lesions that are also found in cattle. Currently, there are no antimicrobial drugs labeled for IVRLP in large animals.
The IVRLP method of antimicrobial delivery offers many advantages over systemic administration. Local administration provides particularly high antimicrobial concentrations at the site of infection and minimizes systemic diffusion and potential side effects. A reduction of the total dose compared with animal bodyweight and minimal systemic plasma concentrations of antimicrobial agents are suitable for decreasing milk levels in lactating dairy cattle. To preserve antimicrobial function, the responsible use of antimicrobial drugs and the procedure of local antimicrobial therapy such as IVRLP in the management of digital septic lesions in cattle are strongly recommended.
Different from systemic administration, IVRLP delivers high antimicrobial concentrations to the digital region with minimal systemic diffusion.
Furthermore, antimicrobial concentrations achieved by systemic administration are often nontherapeutic in a highly septic environment.
Dr. Vincenzo Varasano
Dr. Gianluca Celani
Prof. Dr. Carlo Maria Mortellaro
Dr. Lucio Petrizzi
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- interdigital phlegmon
- deep digital septic condition
- cattle
- intravenous regional limb perfusion
- antibiotics
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
