Transcriptomics in Livestock: Unveiling Genetic Insights for Enhanced Productivity and Health

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Genetics and Genomics".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 947

Special Issue Editors

Animal Functional Genomics and Bioinformatics Lab., Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-do, Korea
Interests: quantitative genetics; functional genomics; system biology, bioinformatics
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Guest Editor
Animal Functional Genomics and Bioinformatics Lab., Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-do, Republic of Korea
Interests: immunogenomics; transcriptomics

E-Mail Website
Guest Editor
Animal Functional Genomics and Bioinformatics Lab., Department of Animal Science and Technology, Chung-Ang University, Anseong, Gyeonggi-do, Republic of Korea
Interests: animal genetics

Special Issue Information

Dear Colleagues,

Transcriptomics, the study of RNA transcripts, has revolutionized our understanding of genetic expression in livestock. By mapping out the complex web of gene activity, researchers can identify key genetic factors that influence productivity and health in farm animals. This field is crucial as it provides insights into improving livestock traits such as growth rates, disease resistance, and overall well-being, which are essential for sustainable agriculture and food security. The following Special Issue aims to bring together cutting-edge research and comprehensive reviews that advance our understanding of transcriptomics in livestock. The focus is on uncovering genetic insights that can be directly applied to enhance productivity and health in various livestock species. By providing a platform for the latest findings, we hope to foster collaborations and drive innovations in livestock genomics. In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Gene expression profiling in different livestock species;
  • The identification of biomarkers for disease resistance and health;
  • Transcriptomic responses to environmental stressors;
  • Comparative transcriptomics across breeds;
  • Functional genomics and gene regulation;
  • The integration of transcriptomics with other 'omics' technologies;
  • The applications of transcriptomics in breeding programs.

We look forward to receiving your contributions.

Dr. Jun-Mo Kim
Dr. Byeonghwi Lim
Dr. Seung-Hoon Lee
Guest Editors

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Keywords

  • transcriptomics
  • RNA-seq
  • gene expression
  • functional genomics
  • gene regulation
  • genomic technologies
  • livestock
  • health
  • productivity

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Published Papers (1 paper)

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Research

16 pages, 769 KiB  
Article
Expression of Genes Related to Meat Productivity, Metabolic and Morphological Significance of Broiler Chickens with the Use of Nutritional Phytochemicals
by Marina I. Selionova, Vladimir I. Trukhachev, Artem Yu. Zagarin, Egor I. Kulikov, Dmitry M. Dmitrenko, Vera N. Martynova, Arina K. Kravchenko and Vladimir G. Vertiprakhov
Animals 2024, 14(20), 2958; https://doi.org/10.3390/ani14202958 - 14 Oct 2024
Viewed by 666
Abstract
The study aimed to analyze gene expression linked to skeletal muscle growth and lipid metabolism in broiler chickens fed with plant extracts. Five groups of chickens were formed: four experimental groups and one control group. The diets of the experimental groups were supplemented [...] Read more.
The study aimed to analyze gene expression linked to skeletal muscle growth and lipid metabolism in broiler chickens fed with plant extracts. Five groups of chickens were formed: four experimental groups and one control group. The diets of the experimental groups were supplemented with different plant extracts: chicory, St. John’s wort, maral root, and creeping thyme, whereas the control group received feed without phytobiotic compounds. Weekly weighings were conducted (n = 36). The chickens were slaughtered at day 26 for tissue sampling of four birds from each group. Gene expression (MYOG, MSTN, FASN) related to muscle growth and fatty acid synthesis was analyzed using the β-actin ACTB gene as a reference. Blood samples were taken at day 35 for biochemical analysis and anatomical dissection was performed. The study revealed that using plant extracts from chicory, thyme, and maral root increased MYOG gene activity by 4.21, 7.45, and 8.93 times, respectively. T. serpyllum extract boosted the MSTN gene by 10.93 times, impacting muscle growth regulation. FASN gene expression for fatty acid synthesis increased significantly by 18.22–184.12 times with plant extracts. The best results regarding meat productivity of chickens were obtained when using R. carthamoides extract. The results of the study will serve as a basis for further development of a phytocomposition designed to increase the meat productivity of broiler chickens in the production of environmentally safe poultry products. Full article
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