Sustainable Recovery of Antioxidants from Natural Sources

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Natural and Synthetic Antioxidants".

Deadline for manuscript submissions: closed (20 July 2023) | Viewed by 17900

Special Issue Editors


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Guest Editor
Chemist III, The State Laboratory, Backweston Laboratory Campus, W23 VW2C Celbridge, Ireland
Interests: extraction of antioxidant phytochemicals; anti-inflammatory and anticarcinogenic properties of phytochemicals; valorization of low-value industrial by-products; application of various separation techniques to purify bioactive compounds for phyto-pharmaceutical and functional food industries
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Guest Editor
Food Innovation Lab, School of Food Science & Environmental Health, Technological University Dublin, 7 Dublin, Ireland
Interests: sustainable bioactives extraction; utilisation; new product development and microbiology and sensory evaluation of food and beverage
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recovery of antioxidants from natural sources using minimal energy, solvents, time, and cost while leaving behind minimal residues is key for the sustainable recovery of antioxidants. Sustainable recovery of antioxidants is very important for our planet and future generations, since the demand for natural antioxidants is continually increasing. A range of novel technologies, such as ultrasound, pulsed electric fields, enzymes, pressurized liquids, and supercritical fluids, are highly relevant for the sustainable recovery of antioxidants. An array of state-of-the-art technologies, such as LC-MS, GC-MS, ICP-MS, and NMR, are available for determining the chemical characteristics of antioxidants. Biological characterizations are achieved through a number of assays, involving prooxidant chemicals, enzymes, cell lines, animal models, and epidemiological studies. Currently, numerous researchers around the globe are working in this field. This Special Issue aims to publish recent studies on the sustainable recovery and characterization of natural antioxidants.

Dr. Mohammad Hossain
Dr. Lubna Ahmed
Guest Editors

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Published Papers (2 papers)

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Research

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12 pages, 2127 KiB  
Article
Individual and Combined Antioxidant Activity of Spices and Spice Phenolics
by Mohammad B. Hossain, Lubna Ahmed, Anna Belen Martin-Diana, Nigel P. Brunton and Catherine Barry-Ryan
Antioxidants 2023, 12(2), 308; https://doi.org/10.3390/antiox12020308 - 28 Jan 2023
Cited by 9 | Viewed by 2672
Abstract
The present study investigated the interaction effects (additive, synergistic, and antagonistic) of different groups of spices, their constituent phenolic compounds, and synthetic antioxidants on the total phenol (TP) content and antioxidant activity, as measured by the ferric-reducing antioxidant power (FRAP) of the mixtures. [...] Read more.
The present study investigated the interaction effects (additive, synergistic, and antagonistic) of different groups of spices, their constituent phenolic compounds, and synthetic antioxidants on the total phenol (TP) content and antioxidant activity, as measured by the ferric-reducing antioxidant power (FRAP) of the mixtures. The results showed that there was an additive effect in all the groups studied, except for the group containing turmeric or curcumin. The groups containing turmeric or curcumin showed a moderate synergistic effect. Among the groups of spices, the highest summated TP (50.6 mg GAE/mL) and FRAP (106.2 mg Trolox/mL) values were observed in the group containing clove, cinnamon, pimento, rosemary, oregano, and cardamom. In the case of the groups of pure phenolics, the highest summated TP (364.96 mg GAE/mL) and FRAP (1124.25 mg Trolox/mL) values were observed in the group containing eugenol, acetyl eugenol, caffeic acid, and protocatechuic acid. The summated and combined TP and FRAP values of the samples correlated highly with the correlation coefficients (r2) of 0.976 and 0.988, respectively, inferring an additive nature of the interaction effect in most of the groups studied. The interactions of phenolics in mixtures are very complex, being affected by a number of factors, and requires more investigations. The current study will add considerable knowledge to the existing literature to understand the diversity and mechanisms of interactions. Full article
(This article belongs to the Special Issue Sustainable Recovery of Antioxidants from Natural Sources)
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Review

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30 pages, 1332 KiB  
Review
Oxidative Stress and Antioxidants—A Critical Review on In Vitro Antioxidant Assays
by Raghavendhar R. Kotha, Fakir Shahidullah Tareq, Elif Yildiz and Devanand L. Luthria
Antioxidants 2022, 11(12), 2388; https://doi.org/10.3390/antiox11122388 - 1 Dec 2022
Cited by 79 | Viewed by 14562
Abstract
Antioxidants have been widely studied in the fields of biology, medicine, food, and nutrition sciences. There has been extensive work on developing assays for foods and biological systems. The scientific communities have well-accepted the effectiveness of endogenous antioxidants generated in the body. However, [...] Read more.
Antioxidants have been widely studied in the fields of biology, medicine, food, and nutrition sciences. There has been extensive work on developing assays for foods and biological systems. The scientific communities have well-accepted the effectiveness of endogenous antioxidants generated in the body. However, the health efficacy and the possible action of exogenous dietary antioxidants are still questionable. This may be attributed to several factors, including a lack of basic understanding of the interaction of exogenous antioxidants in the body, the lack of agreement of the different antioxidant assays, and the lack of specificity of the assays, which leads to an inability to relate specific dietary antioxidants to health outcomes. Hence, there is significant doubt regarding the relationship between dietary antioxidants to human health. In this review, we documented the variations in the current methodologies, their mechanisms, and the highly varying values for six common food substrates (fruits, vegetables, processed foods, grains, legumes, milk, and dairy-related products). Finally, we discuss the strengths and weaknesses of the antioxidant assays and examine the challenges in correlating the antioxidant activity of foods to human health. Full article
(This article belongs to the Special Issue Sustainable Recovery of Antioxidants from Natural Sources)
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