Oxidative DNA Damage and Mechanism of Aging in Insects
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 4621
Special Issue Editor
Interests: Drosophila; development; DNA repair; oxidative stress; aging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recently, many studies have revealed the molecular mechanism of oxidative DNA damage repair, mainly using cultured mammalian cells and unicellular organisms such as yeast and bacteria. Furthermore, other recent studies have argued a relationship between oxidative DNA damage and a progression of aging; although, the theory that the accumulation of reactive oxygen species in internal organs is a major promoter of aging has been considered negatively. However, aging studies using mammalian models take longer to obtain a conclusion. On the contrary, insects have an advantage to studies on oxidative DNA damage at the organism level and the mechanism of aging, due to their rapid growth, shorter lifespan, and lower experimental costs. For example, in the fruit fly Drosophila melanogaster, the most advanced genetic techniques that facilitate experimental investigation at cellular and organism levels have been established. In the past, this organism has been used in many studies to investigate the mechanisms of DNA repair. Recent studies have identified Drosophila orthologs of many essential genes for the repair of DNA damage, including oxidative DNA damage, in other organisms. These findings enhance the value of this organism as a model for investigations on DNA damage repair and aging at the organism level.
Therefore, we have planned a Special Issue entitled “Oxidative DNA Damage and Mechanism of Aging in Insects”. Manuscripts that deal with genes and proteins related to oxidative DNA damage repair and a relationship between oxidative DNA damage and aging that appears in insects are required for submission.
Dr. Yosihhiro Inoue
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- DNA repair mechanisms
- Oxidative stress response
- Ageing
- Insects as models for Oxidative DNA Damage and Mechanism of Aging
- Screening of Antioxidants using Insect models
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
