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Recent Advancement in Technology-Driven Organic Synthesis

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 12029

Special Issue Editor


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Guest Editor
Department of Chemistry, The University of Milan, 20122 Milano, Italy
Interests: new stereoselective metal-free synthetic methodologies; the stereoselective synthesis of chiral pharmaceutical products either by applying ad hoc designed chiral catalysts or by studying and developing innovative stereoselective synthetic methodologies; catalytic stereoselective reactions under continuous-flow conditions in micro- and mesoreactors taking advantage of new enabling technologies such as 3D-printing
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Special Issue Information

Dear Colleagues,

Enabling technology consists of traditional or new techniques whose purpose is to speed up synthetic transformations and workup procedures for the isolation of products. In this framework, flow chemistry, 3D printing devices, and microwave techniques have been rapidly established as essential enabling technologies, not only for academic research but also in industrial chemistry laboratories.

In the last few years, the combination of two or more of these enabling technologies has allowed procedures for the synthesis of target molecules to be sped up and simplified. Synthetic chemists have started to interact and collaborate with chemical engineers to design and build new equipment and devices. From this collaboration and thanks to these enabling technologies, the efficiency of the underlying processes was enhanced, with optimization of the setup process itself. There is no doubt that these enabling technologies will continue to have a strong impact upon the chemical sciences going forward.

For this Special Issue, researchers are invited to submit original research papers related to recent advancement in technology-driven organic synthesis. Topics of interest include but are not limited to the following:

  • Microwave-mediated reactions;
  • Micro- and mesofluidic reactors;
  • Photocatalysis;
  • Deep eutectic solvents;
  • Flow chemistry and catalysis;
  • 3D printing technology;
  • New heating systems;

Dr. Sergio Rossi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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Published Papers (2 papers)

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Research

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11 pages, 2184 KiB  
Article
Quinazolin-4(3H)-ones: A Tangible Synthesis Protocol via an Oxidative Olefin Bond Cleavage Using Metal-Catalyst Free Conditions
by Muhammad Sharif
Appl. Sci. 2020, 10(8), 2815; https://doi.org/10.3390/app10082815 - 18 Apr 2020
Cited by 7 | Viewed by 2746
Abstract
An efficient and selective oxidative procedure for the synthesis of quinazolinones from readily available o-aminobenzamides and styrenes was developed. A number of potentially pharmacologically relevant quinazolinones were prepared using metal- and catalyst-free conditions. The synthesis procedure highlights the sustainable operation, low-priced, free [...] Read more.
An efficient and selective oxidative procedure for the synthesis of quinazolinones from readily available o-aminobenzamides and styrenes was developed. A number of potentially pharmacologically relevant quinazolinones were prepared using metal- and catalyst-free conditions. The synthesis procedure highlights the sustainable operation, low-priced, free from perilous materials, green solvent and environmental affability. The synthesized products were isolated in moderate to excellent yields. Full article
(This article belongs to the Special Issue Recent Advancement in Technology-Driven Organic Synthesis)
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Review

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17 pages, 2754 KiB  
Review
Eosin Y: Homogeneous Photocatalytic In-Flow Reactions and Solid-Supported Catalysts for In-Batch Synthetic Transformations
by Fabian Herbrik, Patricia Camarero González, Milena Krstic, Alessandra Puglisi, Maurizio Benaglia, Miguel A. Sanz and Sergio Rossi
Appl. Sci. 2020, 10(16), 5596; https://doi.org/10.3390/app10165596 - 12 Aug 2020
Cited by 17 | Viewed by 8328
Abstract
In this paper, the most recent and significant applications of Eosin Y as an organo-photocatalyst will be discussed, focusing the attention on enabling technological aspects in homogeneous photochemical flow reactions, as well as on recent developments in solid-supported catalyst applications for batch synthetic [...] Read more.
In this paper, the most recent and significant applications of Eosin Y as an organo-photocatalyst will be discussed, focusing the attention on enabling technological aspects in homogeneous photochemical flow reactions, as well as on recent developments in solid-supported catalyst applications for batch synthetic transformations. Full article
(This article belongs to the Special Issue Recent Advancement in Technology-Driven Organic Synthesis)
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