Multi-omics in Oncology: Discovering Novel Biomarkers and Targets
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cancer Biology".
Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 3921
Special Issue Editor
Interests: mitochondrial medicine; free radical biology; reproduction; cancer biology; chronic diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is a complex ecosystem shaped by tumor cell heterogeneity, interactions with the tumor microenvironment, and spatiotemporal dynamics. Single-cell assays have revolutionized oncology research, allowing for high-resolution mapping of the tumor immune landscape. Technological advancements have also allowed the measurement of diverse histological patterns, such as genomics, epigenomics, transcriptomics, proteomics, metabolomics, and imaging phenotypes. Integration of single-cell and bulk-level multi-omics data from preclinical models and patient samples offers valuable insights into the functioning of the tumor immune ecosystem and responses to therapy, leading to improved biomarkers and treatments.
Multi-omics-based subtype analysis, combining proteomic, phosphorylated proteomic, and genomic analyses of cancer tissues, could potentially unravel the interconnectedness between cancer signaling and crucial metabolic pathways. Topics of this Special Issue include:
- Post-translational modifications in cancer biology;
- Molecular tumor pathology and classification;
- Cancer biomarkers: screening and diagnosis;
- Tumor microenvironment.
Dr. Chia-Jung Li
Guest Editor
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Keywords
- multi-omics
- cancer signaling
- biomarkers
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