Stemness and Differentiation: A Systemic View
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 3613
Special Issue Editors
2. Istituto Nazionale di Alta, Matematica (INdAM), Unit of Messina, Messina, Italy
3. Department of Physics and Earth Sciences, University of Ferrara, 44122 Ferrara, Italy
Interests: solid state physics; crystal lattices; phonon dynamics; magnetic materials and magnetism; magnetic properties; spin waves in confined systems; chemical composition of magnetic materials; magnonic crystals; spintronics; phase transitions; magnetic and seismic metamaterials; superconductivity; high-temperature superconductivity; superfluidity; low-temperature physics; X-ray diffraction; statistical physics and statistical thermodynamics; topological defects; vortices and skyrmions in condensed matter systems; biological physics; biological chemistry; biomathematics and statistical methods applied to medicine; quantum magnetics and acoustic sensors; underwater physics; oceanography; physics of the atmosphere; geophysics; electric distribution networks; electrical engineering and applications
Special Issues, Collections and Topics in MDPI journals
2. Department of General Surgery and Senology, University Hospital Company, 95124 Catania, Italy
Interests: warburg effect; cancer biology; stem cell biology; differentiation processes; gene, epigenic and metabolic networks; glucose catabolism; irreversible reactions; indolic compounds; melatonin; placebo; leukocytes circadian variations; leukocytes
Special Issue Information
During recent years, several studies have demonstrated the key role of the metabolic network in the regulation of gene and epigenetic patterns in the course of self-renewal and differentiation processes. The impact of metabolomics on the remodeling of chromatin and on the regulation of epigenetic expression represents a current topic with new challenges for modern cell biology. In future, more emphasis should be given to the complexity elements linking network hubs during genetic, epigenetic, and metabolic rewiring that accompanies the various steps of cell differentiation. This Special Issue invites original research papers and reviews that cover both modeling and significant experimental advances in uncovering the relationships among the three key networks of life, namely, the metabolic, genetic, and epigenetic networks.
Prof. Dr. Roberto Zivieri
Dr. Nicola Pacini
Guest Editors
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Keywords
- stem cells
- self-renewal
- differentiation
- metabolomics
- epigenomics
- genomics
- complex networks
- statistical mechanics
- probability
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