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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Noncoding RNAs (ncRNAs): The Role in Gene Regulation and Human Diseases

edited by

Liming Chen

and

Yuanshan Zhu

submission deadline 31 Dec 2024 | Viewed by 437 | Submission Open

Keywords: ncRNAs; genomic editing; epigenetics; stem cell biology and regenerative medicine

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advancing Pharmacogenetics in Pre-clinical Research: Unveiling New Avenues for Precision Medicine

edited by

Miriam Saiz-Rodrigez

and

Shengying Qin

submission deadline 31 Dec 2024 | Viewed by 356 | Submission Open

Keywords: pharmacogenetics; pharmacogenomics; precision medicine; individualized medicine

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Novel Progress in Cancer Immunotherapy

edited by

Sheila Spada

submission deadline 31 Dec 2024 | Viewed by 332 | Submission Open

Keywords: immune checkpoint blockers; CAR-T; solid tumor; liquid tumor; cancer therapy; immunology

(This special issue belongs to the Section Cancer Biology and Oncology)

Resistance to Targeted Therapies in Human Cancer, 2nd Edition

edited by

Jeong-yeon Lee

and

Kyung-min Lee

submission deadline 31 Dec 2024 | Viewed by 324 | Submission Open

Keywords: cancer; targeted therapies; drug resistance; biomarkers; anti-cancer drugs; receptor tyrosine kinases; signaling pathways; cancer cell growth; cancer cell survival; anti-tumor effect

(This special issue belongs to the Section Cancer Biology and Oncology)

New Trends in Cancer Immunotherapy

edited by Markella Zannikou

submission deadline 31 Dec 2024 | Viewed by 321 | Submission Open

Keywords: tumor microenvironment; cancer vaccines; tumor-infiltrating lymphocytes; combination therapy; BITEs; checkpoint inhibitors; CAR T cell therapy; NK cells; antigen presenting cells; tumor associated antigens

(This special issue belongs to the Section Immunology and Immunotherapy)

Advances in Cancer Biology and Experimental Anticancer Therapies (2nd Edition)

edited by

Letizia Polito

and

Ewa Gajda

submission deadline 31 Dec 2024 | Viewed by 278 | Submission Open

Keywords: cancer biology; experimental anticancer therapies; immunotherapy; immunotoxins; signalling pathways; targeted therapies

(This special issue belongs to the Section Cancer Biology and Oncology)

Immunosuppressive Treatment in Glomerular Diseases

edited by Henry H.L. Wu and Rajkumar Chinnadurai

submission deadline 31 Dec 2024 | Viewed by 276 | Submission Open

Keywords: immunosuppressive treatment; glomerular diseases; nephrology

(This special issue belongs to the Section Immunology and Immunotherapy)

Recent Advances in Craniofacial Pain and Headaches—Second Edition

edited by

Ignacio Elizagaray-García

and

Alfonso Gil-Martínez

submission deadline 31 Dec 2024 | Viewed by 270 | Submission Open

Keywords: craniofacial pain; headache; migraine; painful temporomandibular disorders; orofacial pain; biomedical advances; treatment; assessment; innovation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Neurotransmitters in Health and Diseases

edited by

Zsolt Bagosi

and Krisztina Csabafi

submission deadline 31 Dec 2024 | Viewed by 265 | Submission Open

Keywords: neurotransmitters; GABA; dopamine; glutamate; acetylcholine; neurohormones; neuromodulators

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Research of Neurodegenerative and Psychiatric Diseases, 2nd Edition

edited by

Dubravka Švob Štrac

submission deadline 31 Dec 2024 | Viewed by 258 | Submission Open

Keywords: neurodegenerative disorders; psychiatric diseases; biomarkers; therapeutic targets; omics approaches; molecular pathways; cell biology; animal models; clinical studies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Hepato-Pancreato-Biliary Cancers: Pathogenesis, Comorbidities and Therapy Updated

edited by

Consolato M. Sergi

and

Paola Di Carlo

submission deadline 31 Dec 2024 | Viewed by 257 | Submission Open

Keywords: liver; bile; cancer; microbiome; pathogenesis; MiRNA; jaundice; disease; therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Poor Ovarian Response: From Bench to Bedside

edited by

Theodoros Kalampokas

submission deadline 31 Dec 2024 | Viewed by 241 | Submission Open

Keywords: assisted reproduction; in vitro fertilization (IVF); poor ovarian response (POR); ovarian functionality; ovarian aging; ovarian stimulation; adjuvant treatment; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Immune Cell Biology: Insights from Molecular Perspectives

edited by

Paolo Fagone

submission deadline 31 Dec 2024 | Viewed by 221 | Submission Open

Keywords: immune cell biology; cell signaling cascades; autoimmune disorders; immunoinflammatory pathways; hematological disorders

(This special issue belongs to the Section Cell Biology and Pathology)

Potential Off-Target Actions of Small-Molecule Modulators Initially Designed for Special Functions

edited by

Sheng-Nan Wu

submission deadline 31 Dec 2024 | Viewed by 219 | Submission Open

Keywords: small-molecule modulators; off-target effects; ion channel modulation; pharmacological impact

(This special issue belongs to the Section Cell Biology and Pathology)

Advancements in the Treatment of Mesothelioma

edited by

Luciano Mutti

submission deadline 31 Dec 2024 | Viewed by 217 | Submission Open

Keywords: mesothelioma; targeted therapy; diagnostics; checkpoint inhibitors; immunotherapy; chemotherapy; combination therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

The Role of MicroRNAs in Adult Skeletal Muscle

edited by Ivan J. Vechetti

submission deadline 31 Dec 2024 | Viewed by 207 | Submission Open

Keywords: skeletal muscle; miRNAs; regeneration; aging; atrophy; hypertrophy

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research on the Role of Biogenic Amines in Physiological and Pathological Conditions

edited by

Pellegrino Lippiello

Luisa Speranza

and

Maria Grazia Ferraro

submission deadline 31 Dec 2024 | Viewed by 197 | Submission Open

Keywords: biogenic amines; memory; synapse; depression; anxiety; schizophrenia; glioma and neurodegenerative diseases

(This special issue belongs to the Section Molecular and Translational Medicine)

New Insights into the Diagnosis and Treatment of Breast Cancer

edited by

Mohammed A. Aleskandarany

and

Weichung Shia

submission deadline 31 Dec 2024 | Viewed by 195 | Submission Open

Keywords: Breast cancer; prognostic; medical imaging; chemotherapy; immunotherapy; diagnostics; screening

(This special issue belongs to the Section Cancer Biology and Oncology)

Extracellular Vesicles in Cancer Progression and Therapeutic Response

edited by

Sheila Spada

submission deadline 31 Dec 2024 | Viewed by 180 | Submission Open

Keywords: nanoparticles; exosomes; engineered EV; immune checkpoint blockade; cancer; microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Innate Immunity Orchestration in Lung Health and Diseases, 2nd Edition

edited by

Meraj Alam Khan

submission deadline 31 Dec 2024 | Viewed by 178 | Submission Open

Keywords: innate immune cells; neutrophils; NETs; NETosis; macrophages; phagocytosis; innate lymphoid cells; epithelial cells; lung inflammation; lung cancer; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Applications and Perspectives of Cold Electric Discharge Plasmas in Biomedicine and Bioengineering

edited by

Andrei Vasile Nastuta

submission deadline 31 Dec 2024 | Viewed by 177 | Submission Open

Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy

(This special issue belongs to the Section Molecular and Translational Medicine)

Extracellular Vesicles and Lipid Nanoparticles in Cardiovascular Diseases

edited by Junlang Li

submission deadline 31 Dec 2024 | Viewed by 175 | Submission Open

Keywords: extracellular vesicles; exosomes: lipid nanoparticles; cardiovascular diseases; RNA delivery

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Molecular Mechanisms and Novel Therapies for Brain Injury: 2nd Edition

edited by

Arjun Sapkota

submission deadline 31 Dec 2024 | Viewed by 165 | Submission Open

Keywords: stroke; spinal cord injury; traumatic brain injury; seizure; brain tumors; neurodegeneration; neuroinflammation; blood– brain barrier disruption; neuroprotection; drug discover; mechanism of action; target validation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Role of Microbiota in Colonic Inflammation and Colon Cancer

edited by

Jianan Zhang

submission deadline 31 Dec 2024 | Viewed by 164 | Submission Open

Keywords: microbiota; colon inflammation; colon cancer; molecular mechanism; clinical treatment

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Crohn’s Disease, the Microbiome and Infections: Mechanisms, Novel Diagnostic and Therapeutic Strategies for Pathology

edited by

Roger Pickup

and

Gaurav Agrawal

submission deadline 31 Dec 2024 | Viewed by 154 | Submission Open

Keywords: infections; gut microbiome; Mycobacterium paratuberculosis; Crohn’ s disease; ulcerative colitis; innate immunity; diagnostics culture; molecular

(This special issue belongs to the Section Cell Biology and Pathology)

Progress in Immunopharmacy

edited by

Po-Jen Chen

and Shun-Hua Chen

submission deadline 31 Dec 2024 | Viewed by 150 | Submission Open

Keywords: immunopharmacy; immunopharmacology; immunomodulation; pharmacological intervention; immunotherapy; drug– immune system interaction; vaccine development; personalized pharmacotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

DNA Methylation Profiling for the Classification and Diagnosis of Tumors

edited by

Valeria Barresi

submission deadline 31 Dec 2024 | Viewed by 150 | Submission Open

Keywords: DNA methylation; tumors; central nervous system; soft tissues; haematolymphoid tumors; diagnostic tool

(This special issue belongs to the Section Gene and Cell Therapy)

Advances of Gut Microbiota in Gastroenterology and Hepatology

edited by

Hsuan-Miao Liu

and

Tzung-Yan Lee

submission deadline 31 Dec 2024 | Viewed by 144 | Submission Open

Keywords: gut microbiota; hepatology; gastroenterology; inflammatory bowel disease; colorectal cancer; nutrition; nature products

(This special issue belongs to the Section Molecular and Translational Medicine)

Immunological Mechanisms of Host Defense and Inflammation: Insights into Immune Responses and Homeostasis

edited by

Rémi Safi

submission deadline 31 Dec 2024 | Viewed by 133 | Submission Open

Keywords: antimicrobial defense; interferon; pro-inflammatory mediators; lipopolysaccharide; immunometabolism; virulence factors; host lipid metabolism; infection; toll like receptors; cytokines

(This special issue belongs to the Section Immunology and Immunotherapy)

Nanomedicine Applications in the Diagnosis and Treatment of Neurodegenerative Diseases

edited by Sudipta Senapati

submission deadline 31 Dec 2024 | Viewed by 125 | Submission Open

Keywords: neurodegenerative diseases; nanomedicine; blood– brain barrier permeability; early diagnosis and treatment; biosensing and bioimaging

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Diseases and Regeneration for Muscle, Joint and Bone

edited by

Chung-Hwan Chen

, Sung-Yen Lin and Cheng-Jung Ho

submission deadline 31 Dec 2024 | Viewed by 121 | Submission Open

Keywords: arthritis; bone; epidemiology; joint; muscle; osteoporosis; pathogenesis; sarcopenia; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Amyloid-β Dynamics and Neurodegeneration: Mechanistic Insights and Therapeutic Strategies

edited by

Rahat Ullah

submission deadline 31 Dec 2024 | Viewed by 113 | Submission Open

Keywords: Alzheimer’ s disease (AD); amyloid-β clearance; brain and periphery; cerebral amyloid angiopathy (CAA)

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Microbiota-Derived Signals in Human Diseases

edited by

Elena Rampanelli

submission deadline 31 Dec 2024 | Viewed by 112 | Submission Open

Keywords: microbiota-derived signals; metabolic diseases; inflammatory diseases

(This special issue belongs to the Section Molecular and Translational Medicine)

Polyamines in Human Diseases

edited by

Kuniyasu Soda

submission deadline 31 Dec 2024 | Viewed by 112 | Submission Open

Keywords: polyamine; spermidine; spermine; health; disease; development

(This special issue belongs to the Section Immunology and Immunotherapy)

Innovations in Nanomedicine for Disease Management

edited by Anna Valentino and

Raffaele Conte

submission deadline 31 Dec 2024 | Viewed by 109 | Submission Open

Keywords: nanomedicine; nanoparticles; smart drug delivery; personalized medicine; minimally invasive treatments; gene therapy; regenerative medicine

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Pathogenesis, Diagnosis, and Treatment of Cardiomyopathy: Special Focus on Infiltrative Cardiomyopathy

edited by Shanat Baig

submission deadline 31 Dec 2024 | Viewed by 98 | Submission Open

Keywords: infiltrative cardiomyopathy; amyloidosis; sarcoidosis; hemochromatosis; Fabry disease; glycogen storage disorders; lysosomal storage disorders; Danon disease

(This special issue belongs to the Section Cell Biology and Pathology)

Applications and Developments of Metal-Based Drugs

edited by

Sajal Sen

submission deadline 31 Dec 2024 | Viewed by 96 | Submission Open

Keywords: anticancer; anti-infectious diseases; nuclear medicines; immunotherapeutic; drug delivery; organometallic complexes; metal-based drugs; metallotherapeutic drugs

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Biliary Tract Cancer: From Molecular Mechanism to Therapeutic Perspectives

edited by Jing Han Hong

submission deadline 31 Dec 2024 | Viewed by 96 | Submission Open

Keywords: biliary tract cancers; molecular mechanisms; drug discovery; therapeutic vulnerabilities; translational science

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Cardiac Fibrosis and Inflammation: Molecular Mechanisms and Therapeutic Frontiers

edited by Melis Olcum

submission deadline 31 Dec 2024 | Viewed by 89 | Submission Open

Keywords: cardiac fibrosis; inflammation; epigenetics; cytokines; inflammasomes; extracellular vesicles; genetic factors; cardiomyopathies; extracellular matrix; fibroblast activation; cardiac biomarker; immune cells; chemokines; heart; in vivo models; in vitro models

(This special issue belongs to the Section Molecular and Translational Medicine)

Ovarian Cancer: From Mechanisms to Novel Target Therapies

edited by

Yi-Hui Wu

submission deadline 1 Jan 2025 | Viewed by 264 | Submission Open

Keywords: epithelial ovarian cancer; relapsed disease; subtypes; therapeutic resistance; metastasis

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art and Novel Approaches in Molecular and Translational Medicine in Europe

edited by

Vasileios Tzounakas

submission deadline 15 Jan 2025 | 6 articles | Viewed by 14669 | Submission Open

Keywords: translational medicine; biomarkers; high throughput techniques; bioinformatics; in vitro and in vivo models; novel therapies; research applications in pathophysiological backgrounds; molecular/biochemical disease characterization

(This special issue belongs to the Section Molecular and Translational Medicine)

The Role of NK Cells in Health and Diseases

edited by Matthew Blunt

submission deadline 15 Jan 2025 | 4 articles | Viewed by 4415 | Submission Open

Keywords: NK cells; lymphoma; multiple myeloma; CLL; AML; leukaemia; immunotherapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Updates on Adrenal Tumors

edited by

Piotr Glinicki

and

Alicja Szatko

submission deadline 15 Jan 2025 | 3 articles | Viewed by 4404 | Submission Open

Keywords: adrenal; neuroendocrine tumor; biomarkers; pheochromocytoma; urinary steroid profile; plasma steroid profile; chromogranin A; granin family protein

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Angiogenesis, Inflammation, and Oxidative Stress in Inflammatory Bowel Diseases

edited by

Mihail Virgil Boldeanu

and Dan Ionuț Gheonea

submission deadline 15 Jan 2025 | 2 articles | Viewed by 2059 | Submission Open

Keywords: inflammatory bowel disease; angiogenesis; inflammation; oxidative stress

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms and Novel Therapeutic Approaches for Arterial and Venous Embolization

edited by Edward W. Lee and Zachary Haber

submission deadline 15 Jan 2025 | Viewed by 356 | Submission Open

Keywords: vascular embolization; new embolic material; tumoral embolization

(This special issue belongs to the Section Cell Biology and Pathology)

Lipids and Lipid Metabolism in Cardiovascular Health and Disease

edited by Fei Luo

submission deadline 15 Jan 2025 | Viewed by 208 | Submission Open

Keywords: lipids; lipoproteins; lipid metabolism; cardiovascular health and disease; atherosclerotic cardiovascular disease; lipid-lowering therapy; triglyceride-lowering therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Mechanisms and Therapeutic Approaches for Oral Disorders

edited by

Vincenzo Ronsivalle

Marco Cicciu

and Simona Santonocito

submission deadline 20 Jan 2025 | 1 articles | Viewed by 795 | Submission Open

Keywords: oral diseases; drugs; local drug delivery; periodontitis; causal periodontal therapy; oral potential malignant disorders; oral cancer; oral medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Approaches in Drug Design: The Pathway from Molecular Mechanisms to New Therapeutic Interventions

edited by

Cristina Manuela Dragoi

Alina Crenguța Nicolae

and

Ion-Bogdan Dumitrescu

submission deadline 20 Jan 2025 | Viewed by 467 | Submission Open

Keywords: drug design; drug development; therapeutic strategies; preclinical and clinical drug research; disease prognosis and response to therapy; drug target discovery; individualized therapy; pharmacogenomics; novel therapeutics; medicinal chemistry; biologics; personalized medicine; precision medicine

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Inherited Retinal Diseases: From Pathomolecular Mechanisms to Therapeutic Strategies

edited by

José Martín-Nieto

submission deadline 31 Jan 2025 | 4 articles | Viewed by 11594 | Submission Open

Keywords: blindness; gene and protein function; pathogenesis; personalized diagnosis; precision therapy; retina; retinal degeneration.

(This special issue belongs to the Section Molecular and Translational Medicine)

Cardiomyopathies and Heart Failure: Charting the Future

edited by Ali Amr

submission deadline 31 Jan 2025 | 5 articles | Viewed by 11564 | Submission Open

Keywords: cardiomyopathies; heart failure; risk stratification; management of cardiomyopathies; cardiac imaging; telemedicine

(This special issue belongs to the Section Molecular and Translational Medicine)

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