The Mechanical Properties of Biomaterials 2.0

A special issue of Biomimetics (ISSN 2313-7673). This special issue belongs to the section "Biomimetics of Materials and Structures".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 11150

Special Issue Editors


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Guest Editor
INM—Leibniz Institute for New Materials, Saarbrücken, Germany
Interests: biological materials; hierarchical structure; bioinspiration; adhesion; wearables
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan, China
Interests: biomaterials and biomineralization; nanomechanics; bioinspired composites
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biomaterials are natural or synthetic materials designed to interact with biological systems for therapeutical purposes. Due to the complexity of the working environment, the mechanical properties of biomaterials are vital for them to endure the erratic stresses imposed by various dynamic stimuli and competently complete the intended tasks, such as sensing or monitoring the tissue lesion, replacing dysfunctional organs, supporting tissue regeneration, or delivering effective medicines. In this regard, we frame this Special Issue in Biomimetics to report the latest advances in studying the mechanical properties of biomaterials, as well as review the recent progress achieved in the related fields. The topics of interest include but are not limited to the following aspects:

  • Mechanical response (stress/strain/time relationships) of biomaterials;
  • Theoretical and experimental fracture mechanics of tissues and implants;
  • The impact behavior of tissues and medical devices;
  • 3D printing of biomaterials and their mechanical properties
  • Adhesion properties of wearable sensors and therapeutic coverings;
  • Tribological study of the interface between biomaterials and human tissues;
  • Advances in the structural and mechanical characterization of biomaterials in both laboratory and clinical scenarios;
  • Mechanobiology, including the response of cells, tissues, and living materials to mechanical stimuli;
  • Bioinspired/biomimetic structural materials for medical applications;
  • Biomineralization processes in mineralized tissues and their effects on mechanical properties.

Dr. Haocheng Quan
Prof. Dr. Wei Huang
Guest Editors

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Keywords

  • natural and synthetic biomaterials
  • mechanical responses
  • fracture mechanics
  • impact resistance
  • adhesion
  • tribology and friction
  • structural characterization
  • mechanical testing
  • mechanobiology
  • bioinspiration/biomimetic
  • biomineralization
  • additive manufacturing

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Published Papers (5 papers)

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Research

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15 pages, 1222 KiB  
Article
Some Mechanical Constraints to the Biomimicry with Peripheral Nerves
by Pier Nicola Sergi
Biomimetics 2023, 8(7), 544; https://doi.org/10.3390/biomimetics8070544 - 13 Nov 2023
Viewed by 1345
Abstract
Novel high technology devices built to restore impaired peripheral nerves should be biomimetic in both their structure and in the biomolecular environment created around regenerating axons. Nevertheless, the structural biomimicry with peripheral nerves should follow some basic constraints due to their complex mechanical [...] Read more.
Novel high technology devices built to restore impaired peripheral nerves should be biomimetic in both their structure and in the biomolecular environment created around regenerating axons. Nevertheless, the structural biomimicry with peripheral nerves should follow some basic constraints due to their complex mechanical behaviour. However, it is not currently clear how these constraints could be defined. As a consequence, in this work, an explicit, deterministic, and physical-based framework was proposed to describe some mechanical constraints needed to mimic the peripheral nerve behaviour in extension. More specifically, a novel framework was proposed to investigate whether the similarity of the stress/strain curve was enough to replicate the natural nerve behaviour. An original series of computational optimizing procedures was then introduced to further investigate the role of the tangent modulus and of the rate of change of the tangent modulus with strain in better defining the structural biomimicry with peripheral nerves. Full article
(This article belongs to the Special Issue The Mechanical Properties of Biomaterials 2.0)
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30 pages, 2992 KiB  
Article
Evaluation of the Mechanical and Physical Properties of Maxillofacial Silicone Type A-2186 Impregnated with a Hybrid Chitosan–TiO2 Nanocomposite Subjected to Different Accelerated Aging Conditions
by Faten K. Al-Kadi, Jwan Fateh Adbulkareem and Bruska A. Azhdar
Biomimetics 2023, 8(7), 539; https://doi.org/10.3390/biomimetics8070539 - 11 Nov 2023
Viewed by 1634
Abstract
The effects of incorporating a pioneer chitosan–TiO2 nanocomposite on the mechanical and physical properties of room-temperature vulcanization (RTV) maxillofacial A-2186 silicone under accelerated aging protocols were rigorously examined. This investigation utilized 450 samples distributed across five distinct silicone classifications and assessed their [...] Read more.
The effects of incorporating a pioneer chitosan–TiO2 nanocomposite on the mechanical and physical properties of room-temperature vulcanization (RTV) maxillofacial A-2186 silicone under accelerated aging protocols were rigorously examined. This investigation utilized 450 samples distributed across five distinct silicone classifications and assessed their attributes, such as tensile strength, elongation, tear strength, hardness, and surface roughness, before and after various accelerated aging processes. Statistical methodologies, including a one-way ANOVA, Tukey’s HSD, and Dunnett’s T3, were employed based on the homogeneity of variance, and several key results were obtained. Silicones infused with 1 wt.% chitosan–TiO2 showed enhanced tensile strength across various aging procedures. Moreover, the 1 wt.% TiO2/Chitosan noncombination (TC) and 2 wt.% TiO2 compositions exhibited pronounced improvements in the elongation percentage. A consistent rise was evident across all silicone categories regarding tear strength, with the 1 wt.% chitosan–TiO2 variant being prominent under certain conditions. Variations in hardness were observed, with the 1 wt.% TC and 3 wt.% chitosan samples showing distinctive responses to certain conditions. Although most samples displayed a decreased surface roughness upon aging, the 1 wt.% chitosan–TiO2 variant frequently countered this trend. This investigation provides insights into the potential of the chitosan–TiO2 nanocomposite to influence silicone properties under aging conditions. Full article
(This article belongs to the Special Issue The Mechanical Properties of Biomaterials 2.0)
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20 pages, 5155 KiB  
Article
Betholletia excelsa Fruit: Unveiling Toughening Mechanisms and Biomimetic Potential for Advanced Materials
by Marilia Sonego, Anneke Morgenthal, Claudia Fleck and Luiz Antonio Pessan
Biomimetics 2023, 8(7), 509; https://doi.org/10.3390/biomimetics8070509 - 26 Oct 2023
Viewed by 1326
Abstract
Dry fruits and nutshells are biological capsules of outstanding toughness and strength with biomimetic potential to boost fiber-reinforced composites and protective structures. The strategies behind the Betholletia excelsa fruit mechanical performance were investigated with C-ring and compression tests. This last test was monitored [...] Read more.
Dry fruits and nutshells are biological capsules of outstanding toughness and strength with biomimetic potential to boost fiber-reinforced composites and protective structures. The strategies behind the Betholletia excelsa fruit mechanical performance were investigated with C-ring and compression tests. This last test was monitored with shearography and simulated with a finite element model. Microtomography and digital and scanning electron microscopy evaluated crack development. The fruit geometry, the preferential orientation of fibers involved in foam-like sclereid cells, promoted anisotropic properties but efficient energy dissipating mechanisms in different directions. For instance, the mesocarp cut parallel to its latitudinal section sustained higher forces (26.0 ± 2.8 kN) and showed higher deformation and slower crack propagation. The main toughening mechanisms are fiber deflection and fiber bridging and pullout, observed when fiber bundles are orthogonal to the crack path. Additionally, the debonding of fiber bundles oriented parallel to the crack path and intercellular cracks through sclereid and fiber cells created a tortuous path. Full article
(This article belongs to the Special Issue The Mechanical Properties of Biomaterials 2.0)
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14 pages, 5408 KiB  
Article
The Flexible Armor of Chinese Sturgeon: Potential Contribution of Fish Skin on Fracture Toughness and Flexural Response
by Yu Zheng, Xin Li, Ping Liu, Ying Chen and Ce Guo
Biomimetics 2023, 8(2), 232; https://doi.org/10.3390/biomimetics8020232 - 2 Jun 2023
Viewed by 1792
Abstract
Fish skin is a biological material with high flexibility and compliance and can provide good mechanical protection against sharp punctures. This unusual structural function makes fish skin a potential biomimetic design model for flexible, protective, and locomotory systems. In this work, tensile fracture [...] Read more.
Fish skin is a biological material with high flexibility and compliance and can provide good mechanical protection against sharp punctures. This unusual structural function makes fish skin a potential biomimetic design model for flexible, protective, and locomotory systems. In this work, tensile fracture tests, bending tests, and calculation analyses were conducted to study the toughening mechanism of sturgeon fish skin, the bending response of the whole Chinese sturgeon, and the effect of bony plates on the flexural stiffness of the fish body. Morphological observations showed some placoid scales with drag-reduction functions on the skin surface of the Chinese sturgeon. The mechanical tests revealed that the sturgeon fish skin displayed good fracture toughness. Moreover, flexural stiffness decreased gradually from the anterior region to the posterior region of the fish body, which means that the posterior region (near the tail) had higher flexibility. Under large bending deformation, the bony plates had a specific inhibition effect on the bending deformation of the fish body, especially in the posterior region of the fish body. Furthermore, the test results of the dermis-cut samples showed that the sturgeon fish skin had a significant impact on flexural stiffness, and the fish skin could act as an external tendon to promote effective swimming motion. Full article
(This article belongs to the Special Issue The Mechanical Properties of Biomaterials 2.0)
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Review

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23 pages, 7147 KiB  
Review
Multifunctionality in Nature: Structure–Function Relationships in Biological Materials
by Jiaming Zhong, Wei Huang and Huamin Zhou
Biomimetics 2023, 8(3), 284; https://doi.org/10.3390/biomimetics8030284 - 2 Jul 2023
Cited by 5 | Viewed by 4538
Abstract
Modern material design aims to achieve multifunctionality through integrating structures in a diverse range, resulting in simple materials with embedded functions. Biological materials and organisms are typical examples of this concept, where complex functionalities are achieved through a limited material base. This review [...] Read more.
Modern material design aims to achieve multifunctionality through integrating structures in a diverse range, resulting in simple materials with embedded functions. Biological materials and organisms are typical examples of this concept, where complex functionalities are achieved through a limited material base. This review highlights the multiscale structural and functional integration of representative natural organisms and materials, as well as biomimetic examples. The impact, wear, and crush resistance properties exhibited by mantis shrimp and ironclad beetle during predation or resistance offer valuable inspiration for the development of structural materials in the aerospace field. Investigating cyanobacteria that thrive in extreme environments can contribute to developing living materials that can serve in places like Mars. The exploration of shape memory and the self-repairing properties of spider silk and mussels, as well as the investigation of sensing–actuating and sensing–camouflage mechanisms in Banksias, chameleons, and moths, holds significant potential for the optimization of soft robot designs. Furthermore, a deeper understanding of mussel and gecko adhesion mechanisms can have a profound impact on medical fields, including tissue engineering and drug delivery. In conclusion, the integration of structure and function is crucial for driving innovations and breakthroughs in modern engineering materials and their applications. The gaps between current biomimetic designs and natural organisms are also discussed. Full article
(This article belongs to the Special Issue The Mechanical Properties of Biomaterials 2.0)
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