Novel Anti-cancer Agents and Their Mechanisms of Action
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 2151
Special Issue Editors
Interests: small-molecule drug discovery; medicinal chemistry; proteolysis-targeting chimeras (PROTACs); targeted protein degradation (TPD); chemical biology; CNS drug discovery
Special Issues, Collections and Topics in MDPI journals
Interests: small-molecule drug discovery; medicinal chemistry; proteolysis-targeting chimeras (PROTACs); targeted protein degradation (TPD); chemical biology; cheminformatics; synthetic organic chemistry
Special Issue Information
Dear Colleagues,
Despite social and technological progress, cancer remains a major concern and a leading cause of human suffering. Every year, there is an increase in the number of cases and deaths due to the ongoing danger posed by the majority of cancers. The alarming rise in incidence of new types of cancer and the public burden represents a real crisis for public health and healthcare systems worldwide. The comprehensive exploration of pathways responsible for, as well as mechanisms and structures of, anticancer chemical entities have significantly contributed in cancer prevention and treatment. The determination of different tumor cell lines, followed by the assessment of the impact of many natural and synthetic anticancer compounds, has resulted in remarkable success. However, major challenges remain, which in the current therapy is the toxicity may be attributed to the use of anticancer agents and the normal tissue damage caused as a consequence. There is a dire need to devise potential anticancer agents with fewer off-target effects. The scope of the present Issue includes novel anticancer compounds from synthetic and natural sources, validated in vitro or in vivo via assessments of their mechanism of actions, or new potential therapeutic strategies for cancer treatment such as proteolysis-targeting chimeras (PROTACs) and combinatorial chemotherapy. It is our pleasure to invite authors to submit original research articles and review articles focused on “Novel Anti-Cancer Agents and Their Mechanisms of Action”.
Dr. Chandra Bhushan Mishra
Dr. Mohd Abdullaha
Guest Editors
Manuscript Submission Information
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Keywords
- novel anticancer agents
- mechanism of action
- synthetic and natural compounds
- PROTACs
- combinatorial chemotherapy
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