Recent Advances in Anti-Tumor Metal Complexes and Drug Delivery Systems: 2nd Edition

A special issue of Biomolecules (ISSN 2218-273X).

Deadline for manuscript submissions: 28 February 2025 | Viewed by 223

Special Issue Editors


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Guest Editor
Faculty of Physical Chemistry, University of Belgrade, Studentski Trg 12-16, 11000 Belgrade, Serbia
Interests: antioxidants and oxidative stress in biological systems; modulators of oxidative stress; structural characterization of novel compounds, new ligands, and their transition metal complexes, with potential biological activity; the inhibitory potential of compounds towards major transport proteins
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Faculty of Physical Chemistry, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia
Interests: transition metal complexes; DFT; noncovalent interactions; DNA and protein binding affinity; spectroscopic characterization; antioxidants; free radicals
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, enhanced intrest in the discovery of novel drugs in order to adequately increase the survival rate of patients with various types of cancer has been observed, as this malignacy is among the most prevalent causes of death worldwide. To overcome all potential problems regarding the application of leading chemotherapeutic agents, such as platinum drugs, a wide range of naturally occurring phytochemicals and their synthetic analogs with anticancer potential are being explored for use in cancer therapy. Signifcant attention has been paid to transition metal complexes other than platinum, which should be more effective and less toxic than the existing ones. Novel, promising perspectives in this area are also associated with the development of so-called “targeted drug delivery systems”, which are created by labeling certain carriers with biologically active molecules or receptors that are specifically attached to targeted cells or tissues.

This Special Issue aims to present recent research regarding the design, synthesis, structural characterization, in silico numerical simulation, and biological activity evaluation of new tumor-selective compounds and their transition metal complexes; this is in addition to their immobilization into drug delivery systems that could provide a therapeutic dose of novel compounds to different cancer cells.

We welcome original research papers and reviews that address novel and naturally occurring phytochemicals or synthetic analogs, their transition metal complexes, and drug delivery systems with possible applications in anticancer therapy.

Prof. Dr. Jasmina Dimitrić Marković
Prof. Dr. Goran Kaluđerović
Dr. Dušan Dimić
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • transition metal complexes
  • synthesis
  • structural characterization
  • biological activity
  • in silico methods
  • drug delivery

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