Growth Factors in Thoracic Cancers
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 3700
Special Issue Editors
Interests: growth factors in cancer; malignant pleural mesothelioma; fibroblast growth factor; activin; optogenetics in cancer research
Interests: surgical oncology; multimodality treatment approaches; minimal invasive surgery; interventional bronchoscopy; experimental targeted therapy in mesothelioma and lung cancer; genomic profiling of mesothelioma and lung cancer; biomarkers
Special Issues, Collections and Topics in MDPI journals
2. Center for Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria
Interests: malignant pleural mesothelioma; small cell lung cancer; fibroblast growth factors in cancer; EMT and cell migration; YB-1; microRNAs in cancer
Special Issue Information
Dear Colleagues,
Growth factors are indispensable signaling molecules for cell communication. They control not only cell growth but numerous additional cell behaviors including differentiation, survival, and migration. Deregulated expression of growth factors is found in many types of cancers and contributes to tumor growth, neoangiogenesis, immune evasion, and metastasis. On the one hand, specific growth factors have become important therapeutic targets and relevant biomarkers in clinical applications. On the other hand, new roles of already well-known growth factors or of hitherto less explored growth factors are constantly being discovered. This Special Issue welcomes work on all aspects of growth factors in thoracic cancers including lung cancer, esophageal cancer, malignant pleural mesothelioma, and thymic malignancies. In all of these cancers, growth factors fundamentally contribute to tumorigenesis not only via cell-autonomous functions but also via the tumor microenvironment. Nevertheless, many aspects of growth factor biology in these cancers and of their application for the benefit of patients still remain to be elucidated. We invite original research papers in the thoracic cancer field addressing growth factor functions, regulation of their expression and secretion, advances in analysis methods, and novel uses as biomarkers and/or therapy targets. Expert reviews discussing any of the above topics are also highly welcome.
Prof. Dr. Michael Grusch
Prof. Dr. Mir Alireza Hoda
Dr. Karin Schelch
Guest Editors
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Keywords
- growth factor
- signal transduction
- biomarker
- therapy target
- lung cancer
- esophageal cancer
- malignant pleural mesothelioma
- thymic malignancy
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