DNA Nanotechnology for Biosensing and Bioimaging
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Nano- and Micro-Technologies in Biosensors".
Deadline for manuscript submissions: closed (31 August 2021) | Viewed by 4608
Special Issue Editors
Interests: DNA nanotechnology; biosensing; Forster resonance energy transfer; drug delivery; nanoparticles
Interests: bionanotechnology; nanoparticle; energy transfer; enzyme; kinetics; cell-free synthetic biology; biocatalysis; bioconjugation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Synthetic DNA nanostructures, assembled from a few to hundreds of orthogonal oligonucleotides, have proven to be chemically addressable and highly programmable for building nanoscale platforms or devices. A wealth of evidence now demonstrates the potential of DNA nanotechnology in nanosensing applications. DNA nanostructures can interact with proteins, indigenous DNA and RNA, gold nanoparticles, quantum dots, DNAzymes, aptamers, and ions, among other molecules, and dynamically reconfigure to give out a reportable signal. DNA-based nanosystems also exemplify signal transduction from organic to inorganic complexes, signal amplification, and in vitro and in vivo biocompatibility. Last, but not least, synthetic DNA is amenable to storage under dried or hydrated conditions, a property that has expanded the diverse scenarios in which it can be transported and used. To that end, they are poised to form the basis of smarter diagnostic and biosensing tools that are modular, rapid, and possess several properties desired for advancing biomedicine.
For this Special Issue, we invite you to submit original research and review articles with a focus on the applications of DNA nanotechnology in biosensing and bioimaging. We welcome research that leverages the versatility of DNA nanotechnology as stand-alone nanosensors or as components that are coupled with physical phenomena such as resonance energy transfer, biological machines such as CRISPR-Cas, or sophisticated engineering in the form of advanced microscopy for biosensing/imaging purposes. DNA nanotechnology also encompasses non-canonical nucleic acids such as peptide nucleic acid and locked nucleic acid, which are emerging as robust alternatives to overcome degradation, and hence are of great interest. Review articles should describe the state of research in the area, the challenges that need to be addressed, and a perspective on the future of the field. We look forward to your contributions.
Dr. Divita Mathur
Dr. Igor Medintz
Guest Editors
Manuscript Submission Information
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Keywords
- Nanomaterials
- DNA origami
- Microscopy
- FRET
- Fluorescence
- Imaging
- Spectroscopy
- CRISPR
- Nanoparticles
- Signal amplification
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