Wearable/Implantable Enzymatic Bioelectronic Devices

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: closed (1 October 2020) | Viewed by 6767

Special Issue Editors


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Guest Editor
Department of Environmental Biology, Sapienza University of Rome, 00185 Roma, Italy
Interests: chemistry of cultural heritage and the environment; soft matters for the cleaning of artistic surfaces and the monitoring of organic polluting species; sensors and biosensors with electrochemical transduction for applications in the environmental, food, and clinical fields; electrochemical techniques for diagnostics of cultural heritage
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Guest Editor
1. Department of Chemistry, University of Bari Aldo Moro, Via E. Orabona, 4-70125 Bari, Italy
2. CSGI (Centre for Colloid and Surface Science), Via E. Orabona, 4-70125 Bari, Italy
Interests: wearable biosensors; biofuel cells; redox polymers; printing enzymes; redox proteins
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Several enzymatic bioelectronic devices have been developed as end-user and time-saving analytical tools to detect many analytes for food, clinical, and environmental applications. Among the big ‘family’ of enzymatic bioelectronic devices, we can certainly include biosensors, biofuel cells, sensing/actuators devices, and lab-on-chip. Enzymes were historically the first molecular recognition elements included in biosensors and continue to be the basis for a significant number of publications in this field. Starting from the very first examples by Clark, Guilbault, and Montalvo, electrochemical transducers combined with enzymes as biochemical components have now became the largest category of biosensors for food, clinical, and environmental sensing.

Recently, all previous research about enzyme-based bioelectronics has been integrated with breakdown achievements on soft wearable/implantable bioelectronics. In particular, enzyme-based bioelectronics, built on diverse biocatalytic reactions, offers distinct advantages and represents a centerpiece of wearable biodevices. Such wearable/implantable bioelectronic devices predominately rely on oxidoreductase enzymes and have already demonstrated considerable promise for on-body applications ranging from highly selective noninvasive biomarker monitoring to epidermal energy harvesting. These systems can thus greatly increase the analytical capability of wearable/implantable devices from the ubiquitous monitoring of mobility and vital signs, toward little to noninvasive analysis of important chemical biomarkers.

This Special Issue, devoted to wearable/implantable enzymatic bioelectronic devices, aims to focus on the most recent advances in the development of wearable/implantable bioelectronic devices from the ubiquitous monitoring of mobility and vital signs, toward little to noninvasive analysis of important chemical biomarkers by using redox enzymes.

Prof. Gabriele Favero
Dr. Paolo Bollella
Guest Editors

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Keywords

  • Enzyme biosensors
  • Enzyme fuel cells
  • Sensing/actuators devices
  • Lab-on-chip
  • Enzyme immobilization
  • Wearable bioelectronics
  • Implantable bioelectronics

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Published Papers (1 paper)

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Research

13 pages, 2535 KiB  
Article
Characteristics of an Extended Gate Field-Effect Transistor for Glucose Sensing Using an Enzyme-Containing Silk Fibroin Membrane as the Bio-Chemical Component
by Kazuto Koike, Taihou Sasaki, Kenta Hiraki, Kodai Ike, Yuichi Hirofuji and Mitsuaki Yano
Biosensors 2020, 10(6), 57; https://doi.org/10.3390/bios10060057 - 29 May 2020
Cited by 19 | Viewed by 6028
Abstract
The characteristics of a glucose sensor based on an ion-sensitive TiO2/Ti extended gate electrode field-effect transistor (EGFET) are reported. A glucose oxidase-containing silk fibroin membrane was immobilized on a TiO2/Ti surface as the bio-sensing component. This EGFET-type biosensor was [...] Read more.
The characteristics of a glucose sensor based on an ion-sensitive TiO2/Ti extended gate electrode field-effect transistor (EGFET) are reported. A glucose oxidase-containing silk fibroin membrane was immobilized on a TiO2/Ti surface as the bio-sensing component. This EGFET-type biosensor was estimated to be able to detect a glucose concentration as low as 0.001 mg/mL in an aqueous electrolyte, which enables the sensing of glucose in the saliva and sweat. The endurance of this sensor was also examined, and it was found that the retention time of the original sensitivity for repeated use at room temperature was more than 30 days, with a high heat tolerance temperature close to 60 °C. Full article
(This article belongs to the Special Issue Wearable/Implantable Enzymatic Bioelectronic Devices)
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