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Cancers
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Advancements in Child, Adolescent, and Young Adult Cancer Survivorship
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Advancements in Child, Adolescent, and Young Adult Cancer Survivorship

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Pediatric Oncology".

Deadline for manuscript submissions: 20 April 2025 | Viewed by 3455

Special Issue Editor

Dr. Juan A. Ortega-García

E-Mail Website
Guest Editor
Paediatric Environmental Health Specialty Unit, Department of Pediatrics, Clinical University Hospital Virgen of Arrixaca, University of Murcia, 30120 Murcia, Spain
Interests: cancer prevention; health-related quality of life; lifestyle; cancer survivors; chronic diseases

Special Issue Information

Dear Colleagues,

We are pleased to announce a Special Issue entitled "Advancements in Child, Adolescent, and Young Adult Cancer Survivorship" to be published in Cancers. As Guest Editor, I am excited to invite you to contribute your valuable research to this significant endeavor.

Childhood cancer survivorship presents unique challenges and opportunities, ranging from long-term health effect surveillance to psychosocial factors influencing quality of life. This Special Issue aims to showcase experiences, models, and approaches in survivorship programs, late effect monitoring, chronic diseases in long-term follow-up, health-related quality of life, resiliency, lifestyles, psychosocial factors, educational and rehabilitation strategies, as well as barriers and disparities in accessing quality care amongst cancer survivors.

We welcome original research articles, reviews, and perspectives that contribute to our understanding of survivorship in pediatric oncology. Submissions should align with the scope outlined above and can cover a wide range of topics within the realm of child, adolescent, and young adult cancer survivorship.

Dr. Juan A. Ortega-García
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • late effects
  • chronic diseases
  • prevention
  • rehabilitation
  • remediation
  • psychosocial factors
  • quality of life
  • lifestyles
  • surveillance
  • survivors
  • educational strategies

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  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
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Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

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Research

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21 pages, 895 KiB  
Article
Assessing the Conceptualizations of Coping and Resilience in LGBTQ2S+ People with Cancer: Working towards Greater Awareness in Cancer Care
by Sarthak Singh, Athina Spiropoulos, Julie Deleemans and Linda E. Carlson
Cancers 2024, 16(17), 2996; https://doi.org/10.3390/cancers16172996 - 28 Aug 2024
Viewed by 633
Abstract
People with cancer may suffer negative psychosocial outcomes due to the challenges of cancer. LGBTQ2S+ people routinely experience negative psychosocial outcomes in health care settings, but have showcased resilience in the face of discrimination; however, this has never been studied in a cancer [...] Read more.
People with cancer may suffer negative psychosocial outcomes due to the challenges of cancer. LGBTQ2S+ people routinely experience negative psychosocial outcomes in health care settings, but have showcased resilience in the face of discrimination; however, this has never been studied in a cancer context. Thus, this study aims to assess coping and resilience in LGBTQ2S+-identifying people diagnosed with cancer using a strengths-based approach. A qualitative exploratory design was used. Ten self-identified LGBTQ2S+ people who have completed their cancer treatment were recruited. Participants completed clinical, health, and demographic questionnaires and, subsequently, semi-structured qualitative interviews. Conceptualizations of coping and resilience in the semi-structured interviews were analyzed using interpretative phenomenological analysis (IPA). Participants were members of various gender identities and sexual orientations. In addition to identifying needed LGBTQ2S+-specific resources, four narratives emerged: support networks, regaining control in life, conflicting identities, and traditional coping methods. Most participants’ cancer journeys were characterized by a ‘Second Coming-Out’ phenomenon, where LGBTQ2S+ people with cancer use coping strategies, similar to those used when coming out, to produce resilience throughout their cancer journey. This work provides exploratory insight into LGBTQ2S+ people with cancer, but more research is required with a larger sample. Full article
(This article belongs to the Special Issue Advancements in Child, Adolescent, and Young Adult Cancer Survivorship)
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13 pages, 2080 KiB  
Article
Telomere Length in Adolescent and Young Adult Survivors of Childhood Cancer
by Meerim Park, Dong-Eun Lee, Yuna Hong, Jin Kyung Suh, Jun Ah Lee, Myungshin Kim and Hyeon Jin Park
Cancers 2024, 16(13), 2344; https://doi.org/10.3390/cancers16132344 - 26 Jun 2024
Viewed by 1180
Abstract
We examined the leukocyte relative telomere length (RTL) in Korean adolescent and young adult (AYA) survivors of childhood cancer and evaluated the association of leukocyte RTL with multiple factors, including malignancy type, cancer treatment, age, and chronic health conditions (CHCs). Eighty-eight AYA survivors [...] Read more.
We examined the leukocyte relative telomere length (RTL) in Korean adolescent and young adult (AYA) survivors of childhood cancer and evaluated the association of leukocyte RTL with multiple factors, including malignancy type, cancer treatment, age, and chronic health conditions (CHCs). Eighty-eight AYA survivors of childhood cancer with a median follow-up period of 73 months were recruited. RTL in pediatric cancer survivors was not significantly shorter than the predicted value for age-matched references. Neither age at diagnosis nor duration of therapy influenced the RTL. Among the 43 patients with hematologic malignancies, those who underwent allogeneic hematopoietic stem cell transplantation (HSCT) showed a significant shortening of the RTL compared with those who did not (p = 0.039). Among the 15 patients who underwent allogeneic HSCT, those who developed acute graft-versus-host disease (GVHD) of grade II or higher had significantly shorter RTL than those who did not (p = 0.012). Patients with grade II CHCs had significantly shorter RTL than those without CHCs or with grade I CHCs (p = 0.001). Survivors with ≥2 CHCs also exhibited shorter RTL (p = 0.027). Overall, pediatric cancer survivors had similar telomere lengths compared to age-matched references. HSCT recipients and patients with severe or multiple CHCs had shorter telomeres. GVHD augmented telomere attrition in HSCT recipients. Full article
(This article belongs to the Special Issue Advancements in Child, Adolescent, and Young Adult Cancer Survivorship)
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18 pages, 1080 KiB  
Systematic Review
Efficacy and Safety of Acupuncture and Related Techniques in the Management of Oncological Children and Adolescent Patients: A Systematic Review
by Esther Martínez García, M. Betina Nishishinya Aquino, Ofelia Cruz Martínez, Yiming Ren, Ruyu Xia, Yutong Fei and Carles Fernández-Jané
Cancers 2024, 16(18), 3197; https://doi.org/10.3390/cancers16183197 - 19 Sep 2024
Viewed by 883
Abstract
Background/Objectives: Oncology acupuncture is emerging as a complementary treatment in pediatric cancer care centers. It is valued for its potential to manage symptoms associated with cancer and treatment toxicities without increasing polypharmacy. The aim of this review is to evaluate [...] Read more.
Background/Objectives: Oncology acupuncture is emerging as a complementary treatment in pediatric cancer care centers. It is valued for its potential to manage symptoms associated with cancer and treatment toxicities without increasing polypharmacy. The aim of this review is to evaluate the efficacy and safety of acupuncture and related techniques in alleviating symptoms of cancer treatment in pediatric oncology patients. Methods: A comprehensive search was conducted across nine databases, including PubMed, Cochrane Library, and CNKI, up to June 2023. Inclusion criteria focused on randomized and quasi-randomized controlled trials involving pediatric oncology patients undergoing needle acupuncture or related techniques. Study selection and data extraction were independently performed by pairs of authors. Results were analyzed narratively, and meta-analysis was performed when possible. Results: Results suggest that acupuncture may help manage symptoms such as nausea and vomiting in pediatric oncology patients. However, the quality of evidence was generally low, and further research is required to substantiate these findings. Conclusions: Acupuncture shows promising results as a complementary treatment for reducing nausea and vomiting in pediatric oncology. However, current evidence is insufficient to draw conclusions for other outcomes, such as the number of vomiting episodes, reduction in antiemetic medication use, or fatigue. High-quality, rigorously designed studies are necessary to better understand the clinical relevance and safety of acupuncture in this vulnerable population. Full article
(This article belongs to the Special Issue Advancements in Child, Adolescent, and Young Adult Cancer Survivorship)
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