Exclusive Review Papers in Parkinson's Research
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Aging".
Deadline for manuscript submissions: 15 December 2025 | Viewed by 136
Special Issue Editors
Interests: botulinum toxin; dystonia; cervical dystonia; sialorrhea; Parkinson’s disease; Blepharospasm
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The diagnosis and therapy of Parkinson's disease have advanced significantly in recent years. While the disease was previously diagnosed purely according to clinical characteristics and differential diagnoses were frequently only possible in the later course of disease, today a valid diagnosis can now be reliably achieved in the preclinical phase. In addition, while these differential diagnoses remained vague and could often only be finally established post-mortem 30 years ago, today they can be performed in the early phase with a high degree of certainty.
A differential therapy was only made possible with the introduction of levodopa in the late 1960s, and numerous medications have since optimized the therapeutic possibilities; however, we continue to only use merely symptomatic treatments with very limited options. Approaches that utilize, for example, alpha synuclein, are still in an early stages of development.
While significant scientific advancements have been achieved, many questions and unresolved problems remain, making the field all the more interesting and intriguing. We have to make our diagnoses early, reliably and validly, and with a justifiable level of effort to achieve differential diagnoses. This will enable us to achieve optimum therapy. We also require novel therapies, which can only be achieved with the performance of high-caliber basic research and the dissemination of information. With this Special Issue, we aim to highlight the current status of research in this field and new ideas and perspectives, as presented by renowned scientists and rising stars.
Prof. Dr. Wolfgang Jost
Prof. Dr. Ronald F. Pfeiffer
Guest Editors
Manuscript Submission Information
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Keywords
- Parkinson’s disease
- alpha-synuclein
- substantia nigra
- mitochondria
- non-motor symptoms
- dopamine
- levodopa
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