Autophagy in Cell Survival and Growth—2nd Edition
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Autophagy".
Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 2279
Special Issue Editor
Interests: autophagy; cell death; cancer; signaling pathway; microbiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autophagy is a "self-digestion" process conserved in eukaryotic cells. During autophagy, intracellular materials (cargo), such as dysfunctional organelles, protein aggregates, lipid droplets, and microbial pathogens, are delivered to the lysosome to be degraded. Based on the transportation method, autophagy can be classified into three main types: macroautophagy, which is the most extensively studied; chaperone-mediated autophagy; and microautophagy.
Autophagy plays a critical role in cellular homeostasis and is associated with the progression of various diseases, such as cancer and neurodegenerative disorders. It primarily supports cell survival, whereby autophagic degradation generates small molecules for biosynthesis and energy production. Recent studies have shown that autophagy promotes cell growth, which refers to an increase in cell numbers, and is regulated by cell proliferation and cell survival.
This Special Issue aims to collect original research and review articles on the underlying mechanisms of the autophagy regulation of cell survival and growth in various eukaryotic cells.
Dr. Yongqiang Chen
Guest Editor
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Keywords
- autophagy
- cell survival
- cell death
- cell growth
- proliferation
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Related Special Issue
- Autophagy in Cell Survival and Growth in Cells (1 article)