Modelling Tissue Microenvironments in Development and Disease
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 10 June 2025 | Viewed by 1817
Special Issue Editors
2. School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, Australia
3. Intelligent Polymer Research Institute and Institute of Innovative Materials, AIIM Facility, Faculty of Engineering and Information Sciences, University of Wollongong, Fairy Meadow, NSW 2519, Australia
Interests: biomedical engineering; regenerative medicine (including stem cells); cancer therapy; medical devices; tissue engineering; tissue modelling
Special Issues, Collections and Topics in MDPI journals
2. School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, Australia
3. Intelligent Polymer Research Institute and Institute of Innovative Materials, AIIM Facility, Faculty of Engineering and Information Sciences, University of Wollongong, Fairy Meadow, NSW 2519, Australia
Interests: regenerative medicine (including stem cells); cancer therapy; medical devices; 3D bioprinting; tissue engineering; tissue modelling
2. School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, Australia
Interests: biomedical engineering; tissue engineering; cancer therapy; 3D bioprinting; micro- and nano-fabrication; mechanobiology
2. School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, Australia
Interests: cancer therapy; 3D bioprinting; biomaterials; tissue engineering; personalized medicine
Special Issue Information
Dear Colleagues,
The microenvironment within tissues is a dynamic determinant of cell behaviour and tissue function, influencing tissue development, organisation, homeostasis, and disease progression. Understanding the microenvironment is therefore important to recreating complex tissue systems in the laboratory and elucidating the mechanisms that govern tissue repair, pathology, and treatment response for new therapeutic opportunities.
This Special Issue, titled “Modelling Tissue Microenvironments in Development and Disease”, aims to showcase advancements in the field. We invite contributions that employ a range of innovative approaches, including three-dimensional (3D) cell culture systems such as self-organising organoids, spheroids, and bioprinted tissues, as well as in silico models.
Key areas of interest include the following:
- The development of novel cell cultures and in silico models that closely mimic healthy and pathological tissue conditions.
- Studies of the roles of different components of the tissue microenvironment, such as the extracellular matrix (ECM), signalling molecules, and physical properties (e.g., mechanical cues), in tissue development and disease progression.
- Application of understanding the tissue microenvironment for drug discovery, toxicology, and regenerative medicine.
By compiling a comprehensive collection of original research articles, reviews, and communications, this Special Issue will serve as a valuable resource for both fundamental/basic and applied research in developmental biology, pathology, tissue engineering, regenerative medicine, and related disciplines.
We look forward to receiving your contributions.
Prof. Dr. Jeremy M. Crook
Dr. Eva Tomaskovic-Crook
Dr. Maryam Alsadat Rad
Dr. Panthipa Suwannakot
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- tissue microenvironment
- developmental biology
- disease biology
- 3D cell culture
- organoids
- spheroids
- bioprinting
- tissue culture
- tissue engineering
- in silico
- extracellular matrix
- mechanobiology
- signalling molecules
- regenerative medicine
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