Cellular Changes in Microgravity and Radiation
A special issue of Cells (ISSN 2073-4409).
Deadline for manuscript submissions: closed (1 June 2020) | Viewed by 4773
Special Issue Editor
Interests: molecular genetics and genomics of stem cells; stem cell cardiovascular genomics; developmental/differentiation; toxicity gene signatures and pathways
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Gravity and radiation have had a great impact on the development of all organisms since the emergence of life. Indeed, mechanical and radiation stimuli mediated by gravity and radiation induce signal transduction pathways, affecting several cellular biological processes such as oxidative stress in various living organisms. During space flights, astronauts are exposed to several major stress stimuli, including microgravity and radiation. Astronauts exposed to microgravity and radiation are suffering from many health-related complications such as loss of bone density, muscle atrophy, and cardiovascular, hematic, metabolic, and endocrine complications, which are all associated with increased senescence. It is hoped that progress in aerospace medical research will minimize the health risks for astronauts. In the long-term, the vision of future space settlement drives several scientific disciplines to investigate the influence of different gravity and radiation conditions on human life and health. This Special Issue will present recent advances on the effects of space radiation and microgravity on cellular functions. Both reviews and original research works are welcome. Manuscripts will undergo a rigorous peer-review process before being accepted for publication.
Prof. Agapios Sachinidis
Guest Editor
Manuscript Submission Information
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Keywords
- microgravity
- radiation
- mechanisms of aging and senescence diseases
- aerospace pharmacology and medicine
- alteration of cellular metabolism
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