Insights into Molecular and Cellular Mechanisms of NeuroCOVID
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".
Deadline for manuscript submissions: closed (20 December 2023) | Viewed by 42636
Special Issue Editors
Interests: NeuroCOVID-19; SARS-CoV-2; post-COVID-19 syndrome; microRNA; RNA-induced silencing complex (RISC); RNA-binding protein; neurodegenerative disease; Alzheimer’s disease; small non-coding RNA; RNA metabolism; cellular and molecular neurobiology; translational biomedicine
Special Issues, Collections and Topics in MDPI journals
Interests: otolaryngology; speech and language pathology; audiology; head and neck surgery; hearing disorders; ENT; rhinology; sleep disorders and sleep medicine; sinusitis; anosmia; neuroCOVID; post-COVID-19
Special Issues, Collections and Topics in MDPI journals
Interests: gut-brain axis; pediatric rare disease; neurophins: BDNF; NGF; anitoxidant and antiinflammatory natural compounds: probiotics and Polyphenols
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Post-COVID-19 syndrome (PCS), or long-haul COVID, is defined by the persistence or recurrence of symptoms after initial SARS-CoV-2 infection. This condition continues for more than 12 weeks and cannot be attributed to other clinical situations. PCS patients are affected by neurological, cardiac, and respiratory symptoms like dyspnea, fatigue, loss of olfactory and taste function with anosmia and dysgeusia, neurocognitive symptoms defined as “brain fog”, sleep disturbance, weakness, and chronic pain reducing physical and mental quality of life. In particular, the brain involvement, and more generally the central and peripheral nervous systems, as potential target organs of SARS-CoV-2 that can be affected during and after infection has been defined as neuroCOVID. Numerous studies have documented neurological and neuropsychological complications, and the effects of COVID-19 on the nervous system are becoming better defined. Now, it is evident that these disorders can also affect young people (30–50 years of age) who 1) had never previously experienced these symptoms, 2) had developed even very mild forms of COVID, or 3) had not experienced breathing problems. The aim of this Special Issue entitled “Insights into Molecular and Cellular Mechanisms of NeuroCOVID” is to explore integrated models of translational biomedical research starting from long-lasting post-infective neurobiological modifications, exploring common molecular and cellular determinants of the neurosensorial and neurological clinical manifestation of this neuroCOVID wave. Original research and review articles from this Special Issue will provide recent molecular and cellular neurobiological findings as well as translational biomedicine studies that highlight working hypotheses, route(s) for SARS-CoV-2 entry to the CNS, relative consequences, post-infective neuropathology, potential relationships with neurodegenerative diseases, and therapy. Researchers and clinicians are allied in unraveling the molecular and cellular pathogenetic mechanisms and the clinical development of this unexpected SARS-CoV-2 infectious evolution, mapping the geography of neuroCOVID.
Dr. Christian Barbato
Prof. Dr. Antonio Minni
Dr. Carla Petrella
Guest Editors
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Keywords
- SARS-CoV-2
- neuroCOVID
- post-COVID-19 syndrome
- neurodegenerative disease
- brain fog
- anosmia
- dysgeusia
- neurocognitive disease
- neurosensorial
- Alzheimer’s disease
- Parkinson’s disease
- non-coding RNA
- neurotherapy
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