Cellular Aspects of Testicular Aging
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Aging".
Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 9301
Special Issue Editors
Interests: testis; ovary; peritubular cells; granulosa cells; granulosa cell tumor
Special Issues, Collections and Topics in MDPI journals
Interests: senescence; testicular aging; cellular model; epigenetics; inflammation; mammalian model; aging germ cells; testicular cells; environmental and endogenous stressors; mitochondrial change and damage
Special Issue Information
Dear Colleagues,
The testis contains stem cells which can fuel life-long spermatogenesis. It is indeed assumed that the testis is able to perform its functions from puberty to the death of an individual. However, it is becoming clear that like all organs of the body, the male gonad also undergoes changes with increasing age, which result in a reduction of its functionality. The advanced age of a father may also have consequences for the offspring. Studies in short-lived animal models are providing important insights into the consequences of testis aging. Yet, in long-lived species, normally occurring changes are difficult to separate from confounding influences. They therefore remain rather challenging to assess.
The purpose of this Special Issue is to cover recent findings about the process and the consequences of testicular aging, including structural and functional changes. We invite all scientists working on the different aspects of aging of the male gonad, particularly aging of its cells (germ cells, somatic cells (including immune cells)) to participate in this Special Issue. Original research articles, reviews, or shorter perspective articles are welcome. Articles with insights from a cellular and molecular biological perspective of mammalian species are especially welcome.
Prof. Dr. Artur Mayerhofer
Dr. Nina Schmid
Dr. Harald Welter
Guest Editors
Manuscript Submission Information
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Keywords
- testis
- aging
- germ cells
- Leydig cells
- Sertoli cells
- peritubular cells
- immune cells
- structure
- epigenetics
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