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Chemosensors
Special Issues
Tenth Anniversary of Chemosensors—"Optical Chemical Sensors" Section
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Tenth Anniversary of Chemosensors—"Optical Chemical Sensors" Section

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Optical Chemical Sensors".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 13464

Special Issue Editors

Prof. Dr. Xiaobing Zhang

E-Mail Website
Guest Editor
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, China
Interests: biosensors; fluorescent molecular probes; nanosensors and functional DNA-based sensors
Special Issues, Collections and Topics in MDPI journals
Dr. Run Zhang

E-Mail Website
Guest Editor
Australian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane 4072, Australia
Interests: analytical chemistry; biosensing and bioimaging; photochemistry; nanotechnology; nano-bio interface chemistry; nanobiosensors; theranostic nanomaterials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are celebrating the 10th anniversary of Chemosensors with a Special Issue in the Section “Optical Chemical Sensors” (IF: 4.229, ISSN 2227-9040) in 2023.

To mark this significant milestone, a Special Issue entitled “Tenth Anniversary of Chemosensors—“Optical Chemical Sensors” Section” is being launched. The Section “Optical Chemical Sensors” focuses on interdisciplinary research, design, the use of new optically active materials and applications with a special interest in multiplexed sensing, as well as low-cost or miniaturized devices and homogeneous sensor platforms. We have published more than 140 papers and have more than 40 Section Board Editors.

The Special Issue covers a wide range of hot topics related to optical chemical sensors. We would like to invite you to contribute an original research paper or a comprehensive review article on a trending or hot topic for peer review and possible publication.

Prof. Dr. Xiaobing Zhang
Dr. Run Zhang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • optoelectronic nose
  • optical materials
  • optical imaging
  • SERS
  • SPR
  • optoelectronic nanosensors
  • spectroscopy
  • optical detection
  • optical probe
  • photoacoustic imaging
  • chemiluminiscence
  • afterglow luminescence

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Published Papers (6 papers)

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Research

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13 pages, 4181 KiB  
Article
Near-Perfect Infrared Transmission Based on Metallic Hole and Disk Coupling Array for Mid-Infrared Refractive Index Sensing
by Lingyi Xu, Jianjun Lai, Qinghua Meng, Changhong Chen and Yihua Gao
Chemosensors 2024, 12(1), 3; https://doi.org/10.3390/chemosensors12010003 - 26 Dec 2023
Viewed by 2123
Abstract
Nanostructured color filters, particularly those generated by the extraordinary optical transmission (EOT) resonance of metal–dielectric nanostructures, have been intensively studied over the past few decades. In this work, we propose a hybrid array composed of a hole array and a disk array with [...] Read more.
Nanostructured color filters, particularly those generated by the extraordinary optical transmission (EOT) resonance of metal–dielectric nanostructures, have been intensively studied over the past few decades. In this work, we propose a hybrid array composed of a hole array and a disk array with the same working period within the 3–14 μm mid-infrared band. Through numerical simulations, near-perfect transmission (more than 99%) and a narrower linewidth at some resonance wavelengths were achieved, which is vital for highly sensitive sensing applications. This superior performance is attributed to the surface plasmon coupling resonance between the hole and disk arrays. A high tunability of the near-perfect transmission peak with varying structural parameters, characteristics of sensitivity to the background refractive index, and angle independence were observed. We expect that this metallic hole and disk coupling array is promising for use in various applications, such as in plasmon biosensors for the high-sensitivity detection of biochemical substances. Full article
(This article belongs to the Special Issue Tenth Anniversary of Chemosensors—"Optical Chemical Sensors" Section)
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11 pages, 1764 KiB  
Article
Speciation of Iron Using Desferal via Simple pH Change and a Single Calibration Curve: High-Throughput Optical Sensor Based on 96-Well Plates and an Overhead Book Scanner as Detector
by Dimitrios Baltzis, Apostolia Tsiasioti, Constantinos K. Zacharis and Paraskevas D. Tzanavaras
Chemosensors 2023, 11(12), 577; https://doi.org/10.3390/chemosensors11120577 - 14 Dec 2023
Cited by 2 | Viewed by 2042
Abstract
In the present study we report the development of an advantageous optical sensor for the speciation of Fe(III)/Fe(II). The sensor is based on the selective reaction of Fe(III) with a Desferal (Deferoxamine) reagent at pH = 2, while both Fe(III) and Fe(II) react [...] Read more.
In the present study we report the development of an advantageous optical sensor for the speciation of Fe(III)/Fe(II). The sensor is based on the selective reaction of Fe(III) with a Desferal (Deferoxamine) reagent at pH = 2, while both Fe(III) and Fe(II) react with the reagent at pH = 5 using an acetate/glycine buffer. In this way, frequently used extra oxidation (H2O2) or reduction (ascorbic acid or hydroxylamine) steps are avoided. Both species can be determined in the range of 25 to 150 μM using a 96-well plate platform and the instrument-free detection of the colored complex with an overhead book scanner. The LOD is 4 μM, and an additional advantage is that a single calibration curve can be utilized for quantitation. The applicability of the sensor was demonstrated by analyzing commercially available pharmaceutical formulations for quality control purposes. Full article
(This article belongs to the Special Issue Tenth Anniversary of Chemosensors—"Optical Chemical Sensors" Section)
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12 pages, 1873 KiB  
Article
Enhanced Fluorescence in a Lens-Less Fiber-Optic Sensor for C-Reactive Protein Detection
by Victoria Esteso, Pietro Lombardi, Francesco Chiavaioli, Prosenjit Majumder, Maja Colautti, Steffen Howitz, Paolo Cecchi, Francesco Baldini, Ambra Giannetti and Costanza Toninelli
Chemosensors 2023, 11(8), 448; https://doi.org/10.3390/chemosensors11080448 - 11 Aug 2023
Cited by 1 | Viewed by 1727
Abstract
In today’s medicine, the celerity of the bio-assays analysis is crucial for the timely selection of the appropriate therapy and hence its effectiveness, especially in case of diseases characterized by the late onset of symptoms. In this paper, a lens-less fiber optics-based fluorescence [...] Read more.
In today’s medicine, the celerity of the bio-assays analysis is crucial for the timely selection of the appropriate therapy and hence its effectiveness, especially in case of diseases characterized by the late onset of symptoms. In this paper, a lens-less fiber optics-based fluorescence sensor designed for the measurement of labeled bio-assays is presented and its potential for the early diagnosis of sepsis via C-reactive protein (CRP) detection is demonstrated. The sensor performance results from the combination of two key elements: a planar antenna that redirects fluorescence the marker emission and an automated fiber-based optical system for multi-spot analysis. First, the working principle of the device is demonstrated with a well-established antibody–antigen format (immunoglobulin IgG/anti-IgG assay), reporting more than one order of magnitude enhanced limit of detection (LOD) and limit of quantification (LOQ) for the planar antenna with respect to a standard glass substrate. The prototype is then tested against a sample mimicking a realistic case, prepared with commercially available human serum, showing a LOD and LOQ in the clinical range of interest (0.0015 μg/mL and 0.005 μg/mL, respectively) for the investigation of the sepsis biomarker CRP. These results validate the developed prototype as a simple and easy-to-operate device, compatible with standardized micro-well arrays, and potentially suitable for POC applications. Full article
(This article belongs to the Special Issue Tenth Anniversary of Chemosensors—"Optical Chemical Sensors" Section)
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17 pages, 3876 KiB  
Article
Locally Enhanced Electric Field Treatment of E. coli: TEM, FT-IR and Raman Spectrometry Study
by Irina Saraeva, Dmitry Zayarny, Eteri Tolordava, Alena Nastulyavichus, Roman Khmelnitsky, Dmitry Khmelenin, Svetlana Shelygina and Sergey Kudryashov
Chemosensors 2023, 11(7), 361; https://doi.org/10.3390/chemosensors11070361 - 27 Jun 2023
Cited by 6 | Viewed by 1936
Abstract
In this paper, we report the study of the low-voltage locally enhanced electric field treatment (LEEFT) of E. coli bacteria via TEM analysis and FT-IR and Raman spectrometry. The formation of pores was confirmed by TEM, which revealed the membrane rupture along with [...] Read more.
In this paper, we report the study of the low-voltage locally enhanced electric field treatment (LEEFT) of E. coli bacteria via TEM analysis and FT-IR and Raman spectrometry. The formation of pores was confirmed by TEM, which revealed the membrane rupture along with the formation of precipitates in the membrane and the cell volume, and by photoluminescence spectra of propidium iodide dye. LEEFT results in the alternation of DNA and RNA structure, indicated by the change in its α-helical and β-helical forms, decrease and narrowing of the nucleic acids-related IR and Raman peaks. Membrane damage is illustrated by the ambiguous character after low-voltage exposure: several membrane fatty acids’ peaks are broadening, while the others narrow, which indicates the overall change of the molecular bonds in their moiety, and may result from the rigidification during the shrinkage of the inner membrane and the increase in fluidity of the outer membrane. The corresponding fingerprints of cytochrome c and bo, located in the membrane or in the periplasm, on Raman spectra, reflect the arising changes in their structure and moiety. The observed changes were partially confirmed by TEM images, which indicate the dense precipitates’ formation in the cell volume and membrane, as well as the cytoplasmic membrane shrinkage away from the outer membrane. Full article
(This article belongs to the Special Issue Tenth Anniversary of Chemosensors—"Optical Chemical Sensors" Section)
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11 pages, 2251 KiB  
Article
Rapid Matching Antibodies Pair and Fast Detecting Melioidosis with Fluorescent Immunochromatographic Test Strips
by Yi-Zhi Lin, Ting-Ting Zhou, Jin Zhu and Shou-Nian Ding
Chemosensors 2023, 11(6), 351; https://doi.org/10.3390/chemosensors11060351 - 19 Jun 2023
Viewed by 1877
Abstract
The high infectivity, difficulty to diagnose, and high drug resistance of melioidosis limited the timeliness of treatment. Lateral flow assay (LFA) was operated in this research to provide an instant diagnosis method, and a fast antibody rapid matching test strategy based on LFA [...] Read more.
The high infectivity, difficulty to diagnose, and high drug resistance of melioidosis limited the timeliness of treatment. Lateral flow assay (LFA) was operated in this research to provide an instant diagnosis method, and a fast antibody rapid matching test strategy based on LFA was developed to select the most sensitive and specific pair of antibodies. Compared to the traditional ELISA method, the new matching strategy limits the pairing time to 3 h without any complex instruments. The rapid pairing test strategy is a universal strategy that is suitable for various sandwich immune antigen pairings. To fasten the test of the test strips, dry fluorescence immunoassay analyzer (DFIA) was designed and applied. The equipment also simplifies the process of data acquisition. Finally, the concentration gradient test was operated, and the detection lines and limits were presented. Full article
(This article belongs to the Special Issue Tenth Anniversary of Chemosensors—"Optical Chemical Sensors" Section)
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Review

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31 pages, 594 KiB  
Review
Spectroscopy, a Tool for the Non-Destructive Sensory Analysis of Plant-Based Foods and Beverages: A Comprehensive Review
by Teodora Basile, Domenica Mallardi and Maria Francesca Cardone
Chemosensors 2023, 11(12), 579; https://doi.org/10.3390/chemosensors11120579 - 18 Dec 2023
Cited by 2 | Viewed by 3168
Abstract
In recent years, there has been a significant rise in the popularity of plant-based products due to various reasons, such as ethical concerns, environmental sustainability, and health benefits. Sensory analysis is a powerful tool for evaluating the human appreciation of food and drink [...] Read more.
In recent years, there has been a significant rise in the popularity of plant-based products due to various reasons, such as ethical concerns, environmental sustainability, and health benefits. Sensory analysis is a powerful tool for evaluating the human appreciation of food and drink products. To link the sensory evaluation to the chemical and textural compositions, further quantitative analyses are required. Unfortunately, due to the destructive nature of sensory analysis techniques, quantitative evaluation can only be performed on samples that are different from those ingested. The quantitative knowledge of the analytical parameters of the exact sample ingested would be far more informative. Coupling non-destructive techniques, such as near-infrared (NIR) and hyperspectral imaging (HSI) spectroscopy, to sensory evaluation presents several advantages. The intact sample can be analyzed before ingestion, providing in a short amount of time matrices of quantitative data of several parameters at once. In this review, NIR and imaging-based techniques coupled with chemometrics based on artificial intelligence and machine learning for sensory evaluation are documented. To date, no review article covering the application of these non-destructive techniques to sensory analysis following a reproducible protocol has been published. This paper provides an objective and comprehensive overview of the current applications of spectroscopic and sensory analyses based on the state-of-the-art literature from 2000 to 2023. Full article
(This article belongs to the Special Issue Tenth Anniversary of Chemosensors—"Optical Chemical Sensors" Section)
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