Recent Development of Bioinformatics Tools of RNA
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Bioinformatics and Systems Biology".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 11396
Special Issue Editor
Special Issue Information
Dear Colleagues,
Recent studies have shown that there are many noncoding RNAs (ncRNAs) that are not translated into proteins but play important roles in various cellular functions. For example, several studies have suggested more long noncoding RNAs (lncRNAs) exist than messenger RNAs in higher eukaryotes including human, and elucidating the functions of these lncRNAs is an urgent task in current molecular biology. On the other hand, various types of RNA-related omics data such as transcriptome (e.g., RNA-seq), epi-transcriptome (e.g., m6A-seq, m1A-seq), structurome (e.g., DMS-seq, SHAPE-seq), and interactome (e.g., CLIP-seq) are accumulating. Integrating these omics data with bioinformatic approaches has also become important in RNA biology. In addition to natural RNAs, artificial RNAs such as RNA aptamers are also attracting attention from researchers as a new generation of target molecules for drug discovery; the computational design of RNA sequences (e.g., RNA aptamer design, RNA inverse folding) is an important problem in this field. This Special Issue covers all aspects of RNA informatics. We welcome papers on both fundamental computational methods for analyzing RNAs and omics data analysis of RNAs.
Dr. Md Mehedi Hasan
Guest Editor
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Keywords
- RNA aptamer
- RNA alignment
- gene expression
- bioinformatics
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